Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury

Conditions:Hospital, Orthopedic
Therapuetic Areas:Orthopedics / Podiatry, Other
Age Range:18 - 64
Start Date:April 2010
Contact:Kayleen M Weaver, BA
Phone:617 573 2196

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Investigation of the Mechanisms of Transcranial Direct Current Stimulation of Motor Cortex for the Treatment of Chronic Pain in Spinal Cord Injury

The purpose of this study is to determine whether the novel treatment of transcranial direct
current stimulation (tDCS) could decrease the pain perception of those with spinal cord

We will also determine whether these changes are correlated with the clinical outcome (pain

The active tDCS stimulation sessions will be compared to sham stimulation.

More study details will be provided by Spaulding Rehabilitation Hospital.

STUDY ELIGIBILITY CRITERIA (similar to the criteria of the Interstitial Cystitis Network)

1. Providing informed consent to participate in the study

2. 18 to 64 years old

3. with traumatic spinal cord injury (complete or incomplete) - for instance, due to
fall, car accident or gun shot; (for spinal cord injury only)

4. stable chronic pain for at least the three preceding months(for spinal cord injury

5. score higher or equal to 4cm (0 cm= 'no pain' and 10cm='worst possible pain') on the
Visual Analogue Scale (VAS) for pain perception at the baseline/start of the
treatment(for spinal cord injury only)

6. refractoriness to drugs for pain relieve - such as tricyclic antidepressants,
antiepileptic drugs and/or narcotics (pain resistant to at least 2 of these drugs
supplied in adequate dosages for six months) (for spinal cord injury only)

7. pain is not attributable to other causes, such as peripheral inflammation.

8. No clinically significant or unstable medical or psychiatric disorder

9. No history of substance abuse

10. No neuropsychiatric comorbidity

11. No implanted devices for pain control, such as vagal or deep brain stimulators

12. No contraindications to tDCS:

- metal in the head

- implanted brain medical devices

13. No pregnancy

14. Eligible to MRI according to MRI screening checklist.

15. No use of ventilators
We found this trial at
300 1st Avenue
Boston, Massachusetts 02129
Spaulding Rehabilitation Hospital At Spaulding Rehabiliation Hospital Boston, our unique approach to therapy includes use...
Boston, MA
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