Comparison of Prasugrel and Clopidogrel in Low Body Weight Versus Higher Body Weight With Coronary Artery Disease
| Status: | Archived |
|---|---|
| Conditions: | Obesity Weight Loss, Peripheral Vascular Disease, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Endocrinology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | March 2010 |
| End Date: | August 2011 |
A Pharmacokinetic and Pharmacodynamic Comparison of Prasugrel and Clopidogrel in Low Body Weight Versus Higher Body Weight Aspirin-Treated Subjects With Stable Coronary Artery Disease
The 5-mg maintenance dose (MD) of prasugrel in low body weight patients with coronary artery
disease produces a pharmacodynamic response within the same therapeutic range as 10-mg MD in
higher body weight patients.
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