Heart Biomarker Evaluation in Apnea Treatment



Status:Archived
Conditions:Insomnia Sleep Studies, Peripheral Vascular Disease, Cardiology, Pulmonary
Therapuetic Areas:Cardiology / Vascular Diseases, Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:February 2010
End Date:April 2011

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Phase II Trial of Sleep Apnea Treatment to Reduce Cardiovascular Morbidity


This study examines the role of sleep apnea treatment in improving cardiovascular
biomarkers.


This is a Phase II randomized controlled trial that will evaluate the effects of
supplemental nocturnal oxygen or Positive Airway Pressure (PAP) therapy, compared to optimal
medical preventive therapy for Cardiovascular Disease (CVD) risk, on biomarkers of CVD risk
in Obstructive Sleep Apnea (OSA) patients at high risk for CVD events. The study will focus
on patients with moderate to severe OSA but only mild OSA symptoms.

Eligible participants have a history or symptoms of heart disease AND have symptoms of sleep
apnea or snoring. Participants will be contributing to medical knowledge about different
options that can be used to improve heart disease in people with sleep apnea.


We found this trial at
4
sites
Boston, Massachusetts 02130
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3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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Boston, Massachusetts 02114
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10900 Euclid Ave
Cleveland, Ohio 44106
216-368-2000
Case Western Reserve Univ Continually ranked among America's best colleges, Case Western Reserve University has...
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Cleveland, OH
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