Long-Term Outcomes in HIV-Infected Infants, Children, and Adolescents



Status:Recruiting
Conditions:HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:Any
Updated:5/27/2013
Start Date:March 2009
End Date:November 2016

Use our guide to learn which trials are right for you!

A Prospective Surveillance Study of Long-Term Outcomes in HIV-Infected Infants, Children and Adolescents


This study will examine the long-term effects of HIV infection, highly active antiretroviral
therapy (HAART), and experimental treatments on children who participated in PACTG 219C or
select IMPAACT studies.


The use of HAART has been important in extending the lives of people with HIV infection.
However, prolonged use of HAART may have long-term consequences. In addition, people
participating in clinical trials using experimental therapies to treat HIV infection may
experience negative health outcomes. The purpose of this study is to identify the long-term
effects of HIV infection, HAART, and experimental treatments in infants, children, and
adolescents.

This study will enroll children who participated in PACTG 219C or various IMPAACT studies.
There will be no study visits specifically for this study. Researchers will review
participants' medical records annually and collect information on illnesses, medications,
CD4 cell count and viral load data, and body measurements.

Inclusion Criteria:

- Past or current documentation of a confirmed diagnosis of HIV-1 infection defined as
two separate peripheral blood specimens from different days, and each specimen must
be positive. More information on this criterion can be found in the protocol.

- HIV-infected infants, children, or adolescents who participated in PACTG 219C during
5/1/06-5/31/07 and are not currently participating in ongoing long-term follow-up
(LTFU) studies (e.g., Pediatric HIV/AIDS Cohort Study Adolescent Master Protocol
[PHACS AMP], LEGACY). Please refer to the IMPAACT website for the current list of
studies or contact the protocol team (actg.teamp1074@fstrf.org).

OR

- HIV-infected infants, children, and adolescents at domestic sites who have
participated in or are currently participating in IMPAACT treatment studies
(including studies that have rolled over from the PACTG into IMPAACT) designated by
the IMPAACT Network Executive Committee (NEC) for subsequent LTFU in this study, and
are not currently participating in ongoing LTFU studies. Please refer to the IMPAACT
website for the current list of studies or contact the protocol team
(actg.teamp1074@fstrf.org).

- Parent or legally-accepted representative/guardian is able and willing to provide
signed informed consent for minors (unless child has emancipated minor status)

Exclusion Criteria:

- Current participation in other ongoing LTFU studies (e.g., PHACS AMP, LEGACY). Please
refer to the IMPAACT website for the current list of studies or contact the protocol
team (actg.teamp1074@fstrf.org).
We found this trial at
37
sites
?
mi
from
Boston, MA
Click here to add this to my saved trials
Baltimore, Maryland 21287
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Bronx, New York 10461
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Chicago, Illinois 60614
?
mi
from
Chicago, IL
Click here to add this to my saved trials
?
mi
from
Denver, CO
Click here to add this to my saved trials
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Durham, North Carolina 27710
?
mi
from
Durham, NC
Click here to add this to my saved trials
?
mi
from
Durham, NC
Click here to add this to my saved trials
?
mi
from
Ft Lauderdal, FL
Click here to add this to my saved trials
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Long Beach, California 90806
?
mi
from
Long Beach, CA
Click here to add this to my saved trials
Los Angeles, California 90054
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Los Angeles, California 90033
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Memphis, Tennessee 38105
?
mi
from
Memphis, TN
Click here to add this to my saved trials
?
mi
from
Miami, FL
Click here to add this to my saved trials
New Orleans, Louisiana 70112
?
mi
from
New Orleans, LA
Click here to add this to my saved trials
New York, New York 10029
?
mi
from
New York, NY
Click here to add this to my saved trials
New York, New York 10016
?
mi
from
New York, NY
Click here to add this to my saved trials
New York, New York 10032
?
mi
from
New York, NY
Click here to add this to my saved trials
?
mi
from
Newark, NJ
Click here to add this to my saved trials
Newark, New Jersey 07103
?
mi
from
Newark, NJ
Click here to add this to my saved trials
?
mi
from
Philadelphia, PA
Click here to add this to my saved trials
?
mi
from
Rochester, NY
Click here to add this to my saved trials
?
mi
from
San Diego, CA
Click here to add this to my saved trials
San Francisco,, California 94117
?
mi
from
San Francisco,, CA
Click here to add this to my saved trials
Seattle, Washington 98105
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Seattle, Washington 98105
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Seattle, Washington 98105
?
mi
from
Seattle, WA
Click here to add this to my saved trials
Stony Brook, New York 11794
?
mi
from
Stony Brook, NY
Click here to add this to my saved trials
?
mi
from
Tampa, FL
Click here to add this to my saved trials
?
mi
from
Washington,
Click here to add this to my saved trials
Washington, District of Columbia 20060
?
mi
from
Washington,
Click here to add this to my saved trials
Worcester, Massachusetts 01605
?
mi
from
Worcester, MA
Click here to add this to my saved trials