Pilot of Acupuncture to Improve Quality of Life in Veterans With Traumatic Brain Injury (TBI) and Post-Traumatic Stress Disorder (PTSD)

Project Background: Acupuncture can be effective for many of the specific co-morbidities
that make up war-related Trauma Spectrum Disorder in both TBI and PTSD patients, including
pain, stress and anxiety, insomnia, somatic and post-operative pain. Recent studies find
very large effect sizes (Cohen's D .85 to 1.4). Thus, there is good reason to believe that
acupuncture will induce recovery across a number of trauma spectrum dysfunctions in patients
with TBI and PTSD, at low cost and with little risk.

Project Objectives: The overall objective of this application is to determine the efficacy
of adjunctive acupuncture for improving quality of life and function and alleviating
co-morbidities associated with TBI and PTSD in service members injured in the current wars.
The primary hypothesis of this study is: OIF/OEF veterans who screen positive for TBI or
PTSD and are treated with a 12 week standard individualized acupuncture method will
experience improved HRQL (as measured by the Veteran's SF-36) at 6, 12 and 24 week
follow-up, compared to veterans randomly assigned to standard care alone.

Project Methods: This is a pilot study on veterans who screen positive for TBI or PTSD in
the VA healthcare record, which is being submitted to obtain additional pilot data,
confirmation of recruitment strategies, information on non-participants and larger
geographic coverage by including sites where the PI already has multisite collaborations.
Frequency distribution and summary statistics for demographics and baseline variables will
be presented by intervention group and for all subjects combined. Key demographic variables
to be summarized are: age, gender, time to deployment, number of deployments, and diagnosis.
Key baseline variables are: PTSD CAPS score, VSF-36, and ANAM score. This two arm pilot
study will lead to a multisite study.