Proteomics Research of Breast Cancer Markers in Interstitial Fluid and Serum



Status:Recruiting
Conditions:Breast Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:2/8/2019
Start Date:September 2009
End Date:February 2021
Contact:Cathy Van Every, BSN
Email:vaneverycc@upmc.edu
Phone:412-781-3744

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The current study is a case control study involving comparisons of tissue interstitial fluid
from breast cancer and adjacent non-cancerous tissue as well as that from benign breast
lesion and its adjacent non-diseased tissue for a distinguishable breast cancer profile. The
purpose of this research is to collect fresh breast nodule/cancer and surrounding
non-cancerous tissue for proteomic studies of the interstitial fluid to identify a profile
distinguishing breast cancer which will also permit future research on stored interstitial
fluid, blood or tissue samples. Specific markers identified from interstitial fluid study
will be investigated in blood samples to develop serum markers for breast cancer diagnosis
and prognosis. Additionally, we will perform both prospective and retrospective research on
breast cancer involving clinical, demographic, epidemiologic information, treatment,
follow-up and outcomes on breast nodule/cancer cases collected.


Inclusion Criteria:

- All subjects ≥ 18 years of age undergoing surgery for indeterminate breast nodules and
all subjects with newly diagnosed breast cancer will be eligible to participate.

Exclusion Criteria:

- Anyone < 18 years of age.
We found this trial at
1
site
Pittsburgh, Pennsylvania 15215
Principal Investigator: Min Sun, MD, PhD
Phone: 412-781-3744
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mi
from
Pittsburgh, PA
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