Dose-dependent Effects of Second-hand Smoke on Vascular Function
| Status: | Archived |
|---|---|
| Conditions: | Peripheral Vascular Disease |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | November 2009 |
| End Date: | June 2010 |
Dose-dependent Biological Mechanisms of Second-hand Smoke on Endothelial Function and Oxidative Stress
The purpose of this study is to determine the vascular effects of brief second-hand smoke
exposure on normal healthy individuals.
Second-hand smoke remains a significant public health threat. Despite evidence to suggest
that secondhand smoke contributes to adverse cardiovascular outcomes, little is known about
the dose-dependent vascular effects of brief secondhand smoke exposure at low doses commonly
encountered in the community. This study will investigate the acute vascular effects and
dose-dependent biological mechanisms of secondhand smoke on endothelial function and
oxidative stress.
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