Effect of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers
| Status: | Archived |
|---|---|
| Conditions: | Alzheimer Disease |
| Therapuetic Areas: | Neurology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | March 2010 |
| End Date: | November 2011 |
A Randomized, Investigator And Subject-Blind, Sponsor-Open, Placebo-Controlled Study To Examine The Effects Of PF-04360365 On ABETA In Patients With Alzheimer's Disease And Healthy Volunteers
The primary goal of this study is to evaluate the effect of PF-04360365 on the clearance of
ABETA from the CSF (cerebrospinal fluid) in patients with mild Alzheimer's disease and
healthy volunteers. Additionally, the study will assess the pharmacokinetics of
PF-04360365, pharmacokinetic and pharmacodynamic relationships in plasma and CSF and the
safety and tolerability of single doses of PF-04360365 administered to patients with
Alzheimer's disease and healthy volunteers.
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