Follicle Stimulating Hormone (FSH) Receptor Polymorphisms in In-Vitro Fertilization Cycles.
| Status: | Archived |
|---|---|
| Conditions: | Women's Studies, Infertility |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | July 2009 |
| End Date: | July 2012 |
The Use of FSH Receptor Polymorphisms To Improve Pregnancy Rates In In-Vitro Fertilization
This study is being done to identify if certain sequences (patterns) of key genes (called
polymorphisms) may predict a response to fertility medications. The investigators will also
determine if the individual response to fertility medications affects pregnancy rates in
in-vitro fertilization.
All IVF patients who meet inclusion criteria and not exclusion criteria will be asked to
participate in this study. Upon consent, a blood sample will be obtained in 2 EDTA
containing lavender topped tubes before, during or within 3 months after their IVF cycle.
Genomic DNA will be extracted and saved for genotyping.
The Investigators will collect data on each individual's age, ethnic background, and
estradiol levels on the day of hCG administration, total gonadotropin amount, clinical
pregnancy rates, basal FSH levels, and occurrence of OHSS. The Investigators will then
analyze all samples from all patients for their FSH receptor genotypes.
Patients will be compensated $75 via a check within 6-8 weeks of their blood drawn.
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