Effect of Age on the Renal Clearance of Adefovir
| Status: | Archived |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
Healthy African American subjects with normal hepatic and renal function will be
administered 10mg adefovir dipivoxil in a fasting state. Subjects will have blood and urine
collections over the following 24 hours for the measurement of adefovir renal clearance. To
investigate the role of age in renal adefovir elimination, 8 subjects will be enrolled from
each of the following age groups: 18-25 years and 48-55 years.
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San Francisco General Hospital San Francisco General Hospital and Trauma Center (SFGH) is an essential...
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