Computed Tomographic (CT) Perfusion and CT Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage



Status:Completed
Conditions:Cardiology, Neurology
Therapuetic Areas:Cardiology / Vascular Diseases, Neurology
Healthy:No
Age Range:18 - Any
Updated:2/7/2015
Start Date:September 2009
End Date:December 2011
Contact:Michelle Miller-Thomas, MD
Email:thomasm@mir.wustl.edu
Phone:314-362-5949

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Trial Summary
Trial Overview
Inclusion Criteria

Computed Tomographic Perfusion and Computed Tomographic Angiography as Screening Tools for Vasospasm Following Subarachnoid Hemorrhage

Cerebral vasospasm is a devastating complication of subarachnoid hemorrhage after cerebral
aneurysm rupture leading to cerebral ischemia and potentially cerebral infarction. The
current gold standard diagnostic imaging study for cerebral vasospasm is catheter cerebral
angiography, an invasive diagnostic procedure carrying a complication rate of 1-2% per
procedure. Computed tomographic perfusion imaging (CTP) and computed tomographic
angiography (CTA) are noninvasive diagnostic imaging studies frequently utilized in the
evaluation of embolic and thrombotic cerebral infarct. The investigators hypothesize that
CTP and CTA may be utilized as screening tools for cerebral vasospasm following aneurysmal
subarachnoid hemorrhage requiring treatment and provide prognostic information.


Inclusion Criteria:

- subarachnoid hemorrhage after aneurysm rupture

Exclusion Criteria:

- renal insufficiency

- pregnancy

- contrast reaction
We found this trial at
1
site
Barnes Jewish Hospital
1 Barnes Jewish Hospital Plaza
St. Louis, Missouri 63110
(314) 747-3000
Barnes Jewish Hospital Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in...
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from
St. Louis, MO
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