A Long Term Extension Study Evaluating ACC-001 With QS-21 in Subjects With Mild to Moderate Alzheimer's Disease



Status:Terminated
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:50 - 85
Updated:4/21/2016
Start Date:July 2009
End Date:December 2013

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A Phase 2a, Multicenter, Randomized, Third-party Un-blinded, Long-term Extension Study To Determine Safety, Tolerability, And Immunogenicity Of Acc-001 With Qs-21 Adjuvant In Subjects With Mild To Moderate Alzheimer Disease

The purpose of this study is to assess the long term safety, tolerability, and
immunogenicity of ACC-001, an investigational vaccine, plus QS-21 in subjects with mild to
moderate Alzheimer's disease.


Inclusion Criteria:

Subjects randomized under previous 3134K1-2201 study (NCT00498602) and met all
inclusion/and none of the exclusion criteria.

Screening brain MRI scan is consistent with the diagnosis of AD.

Mini-Mental State Examination (MMSE) score greater than or equal to 10.

Other criteria apply.

Exclusion Criteria:

Significant Neurological Disease other than Alzheimer's disease.

Current clinically significant systemic illness.

Other exclusion criteria apply.
We found this trial at
22
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20 York St, N20 York St,
New Haven, Connecticut 06520
(203) 688-4242
Yale-New Haven Hospital Relying on the skill and expertise of more than 4,500 university and...
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911 E. Hallandale Beach Blvd
Hallandale Beach, Florida 33009
954-455-5757
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Bennington, Vermont 05201
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Bennington, Vermont 05201
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Bennington, Vermont
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Boston, Massachusetts 02215
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Boston, Massachusetts 02115
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Eatontown, New Jersey 07724
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333 Cedar St
New Haven, Connecticut 06504
(203) 432-4771
Yale University School of Medicine Founded in 1810, the Yale School of Medicine is a...
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New York, New York 10032
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New York, New York 10032
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Phoenix, Arizona 85006
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345 Blackstone Blvd
Providence, Rhode Island 02906
(401) 455-6200
Butler Hospital Founded in 1844, Butler Hospital is the state's only non-profit, free-standing psychiatric hospital...
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San Francisco, California 94143
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1 Barnes Jewish Hospital Plaza
St. Louis, Missouri 63110
(314) 747-3000
Barnes Jewish Hospital Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in...
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St. Louis, Missouri 63108
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Sun City, Arizona 85351
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Sun City, Arizona 85351
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Washington, District of Columbia 20007
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3800 Reservoir Rd NW
Washington, District of Columbia 20007
(202) 687-7695
Georgetown University Medical Center Georgetown University Medical Center is committed to excellence in research, education...
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