Early Connections, Early Detection and Intervention in Infants at Risk for Autism



Status:Completed
Conditions:Neurology, Psychiatric, Autism
Therapuetic Areas:Neurology, Psychiatry / Psychology
Healthy:No
Age Range:Any
Updated:4/2/2016
Start Date:January 2008
End Date:July 2012
Contact:Vanessa Rivera
Email:ddrinfo@u.washington.edu
Phone:1-800-994-9701

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UW ACE Project II, Early Detection and Intervention in Infants at Risk for Autism

Early connections has two broad goals:

- to identify risk indices for autism spectrum disorder (ASD) in 6 to 24 month old
infants who have an older sibling with ASD or infants who have an older neurotypical
sibling.

- to assess whether it is possible to alter risk processes through early intervention
with high-risk infants, thereby reducing social-communication delays or the severity of
autism symptoms.

Researchers at the University of Washington want to learn more about the benefits of early
monitoring and intervention for younger siblings of children with autism spectrum disorders
(ASD). The information gained in this study may improve methods of early detection and
intervention for infants who may be at risk for developing autism and lead to better outcome
for these young children and their families.

Participants include families with a child who has been diagnosed with an autism spectrum
disorder or typical development and a younger sibling 12 months old or younger. The study
protocol includes: (1) comprehensive infant evaluations at the University of Washington
Autism Center at 6-months, 12-months, 18-months and 24-months of age. (2) Developmental
screening for the older sibling. (3) Questionnaires and phone interviews for parents. (4)
Random assignment to an assessment and monitoring intervention group or a University of
Washington intervention group. All families will receive advice regarding appropriate
intervention services. Families who are assigned to the UW intervention will take part in a
parent delivered intervention.

Inclusion Criteria:

- Older sibling with ASD (biologically related to participant)

- Participant 12 months of age or younger

- Within 1 hour of University of Washington

- Interested in participating in Intervention

Exclusion Criteria:

- Out of study area

- Serious parent substance abuse or psychiatric history

- Diagnosis of known genetic syndromes or neurological conditions (infant participant
or older sibling)

- Serious motor impairment (infant participant)

- Significant prematurity (infant participant)
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