Structure and Function of Salivary Proteins
| Status: | Recruiting |
|---|---|
| Conditions: | Pulmonary |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 6 - Any |
| Updated: | 4/2/2016 |
| Start Date: | November 2007 |
| Contact: | Lamia Momen |
| Email: | lamia.momen@childrens.harvard.edu |
| Phone: | 617-355-6665 |
This study seeks to provide point-of-care clinical diagnostic systems for the diagnosis of
current disease status using saliva as a sample specimen.
current disease status using saliva as a sample specimen.
The overall hypothesis of this study is that whole saliva and its components, due to its
direct anatomic relation to the airways, provides a window on the composition and nature of
the disease-specific response in the bronchial, sinus, and nasal airways. By examining
proteins created in saliva, we hope to validate that saliva is an important diagnostic tool
for for rapid analysis of respiratory status. We further propose that rapid salivary
diagnostics will improve patient care in prevalent respiratory diseases with frequent health
care utilization and high morbidity, such as asthma, chronic obstructive pulmonary disease
(COPD), and cystic fibrosis (CF).
direct anatomic relation to the airways, provides a window on the composition and nature of
the disease-specific response in the bronchial, sinus, and nasal airways. By examining
proteins created in saliva, we hope to validate that saliva is an important diagnostic tool
for for rapid analysis of respiratory status. We further propose that rapid salivary
diagnostics will improve patient care in prevalent respiratory diseases with frequent health
care utilization and high morbidity, such as asthma, chronic obstructive pulmonary disease
(COPD), and cystic fibrosis (CF).
Inclusion Criteria:
- 6 or more years of age
- confirmed Cystic Fibrosis
Exclusion Criteria:
- Pregnant
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