Collecting and Storing Blood Samples From Patients With Cancer

OBJECTIVES:

- To establish a repository for long-term storage of DNA obtained from patients treated
at the Cancer Institute of New Jersey.

- To establish a mechanism whereby investigators can analyze correlations between genetic
polymorphisms and clinical outcomes (e.g., response to treatment).

OUTLINE: Additional blood samples are collected for banking from patients while they are
scheduled for routine blood draw as a part of their normal care. Samples are stored in a
secure place under the control of the Cancer Institute of New Jersey Tissue Retrieval
service. The samples may be used for DNA, RNA, or protein extraction and analyses, as well
as generation of cell lines.

Demographic data (ethnicity, race, age, and sex), diagnosis, family history, and previous
treatments (chemotherapy, radiation, and surgery) are recorded on the case report form and
kept in a secure location in the Office of Human Research Services (OHRS).

Patients may have their samples removed and destroyed at any time.