Studying Tumor Tissue Samples and Blood Samples to Learn More About DNA Changes in Patients With Lung Cancer

OBJECTIVES:

- Examine the mutational status of the EGFR pathway in tumor and blood samples from
patients with lung cancer.

- Correlate the EGFR pathway mutations in these samples with clinical outcomes of these
patients.

OUTLINE: Archived tumor tissue and blood samples are analyzed via PCR to detect EGFR pathway
mutations in DNA.

DISEASE CHARACTERISTICS:

- Histologically or cytologically confirmed lung cancer

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- May have received prior EGFR inhibitors