Study Comparing 3 Dosage Levels of SAM-531 in Outpatients With Mild to Moderate Alzheimer Disease.



Status:Archived
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:April 2009
End Date:June 2011

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A 52-week, 2-period, Multicenter, Randomized, Double-blind, Donepezil-referenced, Placebo-controlled, Efficacy, and Safety Study of 3 Dosage Levels of SAM-531 in Outpatients With Mild to Moderate Alzheimer Disease.


The study will evaluate the efficacy and safety of an investigational drug called SAM-531 at
three dosage levels. Subjects will receive either SAM-531, donepezil or placebo for the
first 24 weeks of the study (period I). Subjects who receive placebo for period 1 will be
assigned to receive SAM-531 for the remaining 28 weeks of the study, while subjects who
received one of the three SAM-531 dosage levels or donepezil in period I will continue with
the same study drug (period II).



We found this trial at
20
sites
Mountlake Terrace, Washington
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Mountlake Terrace, WA
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Albany, New York
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Albany, NY
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Atlanta, Georgia
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Atlanta, GA
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Austin, Texas
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Austin, TX
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Bismarck, North Dakota 58501
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Bismarck, ND
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Burlington, Vermont
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Burlington, VT
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Celebration, Florida
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Celebration, FL
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Centralia, Illinois
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Centralia, IL
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Denver, Colorado
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Denver, CO
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Lima, OH
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Little Rock, Arkansas
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Little Rock, AR
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Medford, Oregon
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Medford, OR
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Milwaukee, Wisconsin
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Milwaukee, WI
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Nashville, Tennessee
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Nashville, TN
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Peoria, Arizona
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Peoria, AZ
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Philadelphia, Pennsylvania
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Philadelphia, PA
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Ponca City, Oklahoma
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Ponca City, OK
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Santa Clara, California 95051
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Santa Clara, CA
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St Louis, Missouri
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St Louis, MO
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West Orange, New Jersey
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West Orange, NJ
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