Effect of Lactobacillus Rhamnosus GG (LGG) on Infant Colic
Status: | Completed |
---|---|
Healthy: | No |
Age Range: | Any |
Updated: | 4/21/2016 |
Start Date: | September 2011 |
End Date: | January 2013 |
Effect of Lactobacillus Rhamnosus GG (LGG) on Infant Crying, Intestinal Microbiota, and Intestinal Inflammation in Infants With Colic
This study will compare 2 currently marketed formulas in healthy full term babies:
Nutramigen A+ (a hypoallergenic formula) and Nutramigen-Enflora (hypoallergenic formula with
Lactobacillus GG (LGG)) during 3 months of formula feeding. The investigators' aims are to
compare 3 outcomes in these babies: (1) normal baby crying time; (2) the composition of
intestinal microbiota (bacteria in the stool); and (3) a lab test which measures the number
of white blood cells in the large intestine (fecal calprotectin). The investigators predict
that LGG supplementation (Nutramigen-Enflora) will facilitate its establishment as an
important component of the neonatal intestinal microbial community and reduce fecal
calprotectin.
Nutramigen A+ (a hypoallergenic formula) and Nutramigen-Enflora (hypoallergenic formula with
Lactobacillus GG (LGG)) during 3 months of formula feeding. The investigators' aims are to
compare 3 outcomes in these babies: (1) normal baby crying time; (2) the composition of
intestinal microbiota (bacteria in the stool); and (3) a lab test which measures the number
of white blood cells in the large intestine (fecal calprotectin). The investigators predict
that LGG supplementation (Nutramigen-Enflora) will facilitate its establishment as an
important component of the neonatal intestinal microbial community and reduce fecal
calprotectin.
Inclusion Criteria:
- Sixty healthy full-term colicky infants (gestational age 32 wks to 41 wks)
Exclusion Criteria:
- chronic lung disease,
- diarrhea (stools that take the shape of a container > 5x daily)
- fever
We found this trial at
1
site
7000 Fannin St
Houston, Texas 77030
Houston, Texas 77030
(713) 500-4472

University of Texas Health Science Center at Houston The University of Texas Health Science Center...
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