A 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet
| Status: | Archived |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | October 2010 |
An Open-Label, 3-Part Study to Determine the Relative Bioavailability of Capsule and Tablet Formulations of GDC-0980, the Effect of Food, and the Effect of Rabeprazole on the Pharmacokinetics of the Tablet
This will be a single-center, open-label, 3 part study. The study is designed to determine
the relative bioavailability of GDC-0980 capsule and tablet formulations under fasting
conditions, the effects of a high-fat (fed) meal on the pharmacokinetics of the GDC-0980
tablet, and the effects of rabeprazole on the pharmacokinetics of the GDC-0980 tablet in the
presence or absence of a high-fat meal.
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