Study of Heart Effects When Growth Hormone (GH) is Used for Growth Hormone Deficiency (GHD) Following Cure of Acromegaly
| Status: | Recruiting |
|---|---|
| Conditions: | Skin Cancer, Endocrine |
| Therapuetic Areas: | Endocrinology, Oncology |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 5/27/2013 |
| Start Date: | February 2011 |
| Contact: | Eleanor Lin, MD |
| Phone: | 617-726-3897 |
Effects of Physiologic Growth Hormone Administration on Echocardiographic Parameters in Subjects With Growth Hormone Deficiency Following Cure of Acromegaly
Having too little or too much GH are both associated with heart disease.
The purpose of this research study is to study the effects of growth hormone (GH)
replacement on the heart. We will study these effects in people who have been cured of
acromegaly and then have developed growth hormone deficiency (GHD, not enough growth
hormone).
Inclusion Criteria:
- age 18-75
- history of acromegaly with biochemical cure
- growth hormone deficiency
Exclusion Criteria:
- untreated thyroid disease within the past 3 months
- untreated adrenal insufficiency within the past 3 months
- uncontrolled hypertension
- congestive heart failure
- gonadal steroid therapy within the past 3 months
- pregnancy or nursing
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