Drug-drug Interaction Study of Aggrenox and Omeprazole in Normal Volunteers



Status:Archived
Conditions:Healthy Studies
Therapuetic Areas:Other
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:March 2011

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Drug-drug Interaction Study of the Effect of Omeprazole 80 mg q.d. at Steady State on the Pharmacokinetics and Pharmacodynamics of Aggrenox® Every 12 Hours at Steady State in Healthy Male and Female Volunteers (an Open-label, Randomised, Crossover Study)


The objective of the current study is to investigate if a drug-drug interaction occurs with
the administration of omeprazole 80 mg q.d. at steady state on the pharmacokinetics of
dipyridamole and the pharmacodynamics of ASA-induced platelet aggregation inhibition
(components of Aggrenox®) when administered every 12 hours at steady state.


Purpose:


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