Genetics Study of Wet Age-Related Macular Degeneration (AMD) Non-Responders to Vascular Endothelial Growth Factor (VEGF) Therapy



Status:Active, not recruiting
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:Any
Updated:10/14/2018
Start Date:April 2011
End Date:June 2019

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Genotypic Evaluation of Chronic Exudative Macular Degeneration Despite Monthly Anti-Vascular Endothelial Growth Factor (VEGF) Therapy

To obtain a genotypic analysis of patients with chronic exudative age-related macular
degeneration noted to have subretinal or intraretinal edema despite continuous monthly
Anti-VEGF therapy.


Inclusion Criteria:

- Ability to provide written informed consent for participation in this study

- Subjects diagnoses of neovascular AMD who are on a monthly anti-VEGF regimen (have had
>10 or more ranibizumab and/or bevacizumab injections within the last year) and who
still have intra-retinal or subretinal fluid as confirmed by the Investigator

Exclusion Criteria:

- Subjects with a Pigment Epithelial Detachment Exclusively

- Subjects with Serous Pigment Epithelial Detachments

- Subjects with history of the following:

idiopathic polypoidal choroidal vasculopathy

- pathologic degenerative myopia

- central serous chorioretinopathy

- familial drusen

- adult onset foveal pattern dystrophy
We found this trial at
1
site
San Francisco, California 94107
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from
San Francisco, CA
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