Low Intensity Resistance Training With Partial Blood Flow Restriction for Quadriceps Strengthening

The objective of the proposed research is to assess the efficacy of an eight-week, efficient
and tolerable, low-intensity resistance-training program with concurrent application of
partial blood flow restriction (PBFR) for improving quadriceps strength and volume in women
with risk factors for incident symptomatic or progressive knee OA. This specific aim will be
achieved through a randomized, controlled trial, comparing low intensity training with and
without PBFR. There have been numerous reports of exercise interventions in people with knee
osteoarthritis. However, this research is novel in that it will be the first to use a low
intensity regimen that will minimize forces on the knee while still having the potential to
lead to clinically meaningful strength gains in older adults with risk factors for incident
symptomatic or progressive knee OA.