Photosensitivity Proof of Concept Trial



Status:Archived
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:May 2009
End Date:March 2010

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Assessment of Marketed AEDs in the Human Photosensitivity Proof of Concept Trial


The purpose of this study is to determine whether patients who usually have abnormal
electrical EEG responses when shown flashing lights will show a reduction in abnormal
electrical activity when they take a single dose of 2 marketed drugs (carbamazepine and
levetiracetam). If so, a similar study in the future may be able to identify promising new
drugs for epilepsy.

Patients who successfully complete the screening visit, will return 4 additional times and
will receive either placebo (2 times) or a single oral dose of both carbamazepine 400mg and
levetiracetam 1000mg in random order.

During each of the study days, several procedures and intermittent photosensitivity (IPS)
assessments will be performed at 5 pre-determined times over the course of the day, one
pre-dose and 4 post-dose.



We found this trial at
2
sites
550 1st Ave
New York, New York 10016
(212) 263-7300
New York University Langone Medical Center NYU NYU Langone Medical Center, a world-class, patient-centered, integrated,...
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New York, NY
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3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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Baltimore, MD
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