Quetiapine Extended Release (XR) Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder



Status:Archived
Conditions:Anxiety, Depression, Major Depression Disorder (MDD), Psychiatric
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:June 2008
End Date:March 2012

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Quetiapine XR Monotherapy or Adjunctive Therapy to Antidepressants in the Treatment of Major Depressive Disorder With Comorbid Generalized Anxiety Disorder


The primary objective is to test the hypothesis that quetiapine XR (Extended Release)
monotherapy or adjunctive therapy to antidepressant is superior to placebo monotherapy or
placebo adjunctive therapy to antidepressant(s) in the acute treatment of depression
symptoms in patients with MDD and comorbid GAD. The secondary objectives are to test the
hypotheses that quetiapine XR is superior to placebo in the reduction of anxiety symptoms in
patients with major depressive disorder and comorbid generalized anxiety disorder, the
improvement of the quality of sleep in patients with major depressive disorder and comorbid
generalized anxiety disorder and the improvement of the quality of life in patients with
major depressive disorder and comorbid generalized anxiety disorder.



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1
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10900 Euclid Ave
Cleveland, Ohio 44106
216-368-2000
Case Western Reserve Univ Continually ranked among America's best colleges, Case Western Reserve University has...
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Cleveland, OH
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