Sedation and Pain (The Effect of IV Sedation on Pain Perception)
| Status: | Archived |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | November 2008 |
| End Date: | November 2010 |
The investigators propose to evaluate the potential effect of sedation on pain perception in
two ways, by asking for a participant's pain rating(subjective) and by evaluating a
subject's brain activation using fMRI(objective).
We propose to contrast and compare the effect of propofol and midazolam, two GABA-related
sedative drugs, and dexmedetomidine, an alpha-2 adrenergic agonist, on pain perception in
human volunteers by asking a participant to rate their pain and by evaluating a subject's
brain activation using fMRI.
We found this trial at
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University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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