Pharmacodynamic/Pharmacokinetic Study of AQW051 in Schizophrenia



Status:Archived
Conditions:Schizophrenia
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:January 2009

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A Single-dose, Placebo-controlled, Stratified, Randomized, Double-blind, Crossover to Study Pharmacodynamic Effects of AQW051 Followed by a 4-week Multiple-dose Safety and Tolerability in People With Chronic Stable Schizophrenia.


Part 1 of the study will assess the enhancement of task-related brain activation (BOLD
response) in key brain areas in schizophrenia during the performance of working memory,
episodic memory and visual activation tasks as measured by functional magnetic resonance
imaging (fMRI) in people with schizophrenia. Part 2 of the study will assess the safety and
tolerability of multiple doses of AQW051 in people with schizophrenia.



We found this trial at
7
sites
Butner, North Carolina 27509
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Butner, NC
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1 Brookings Drive
St. Louis, Missouri 63110
 (314) 935-5000
Washington University Washington University creates an environment to encourage and support an ethos of wide-ranging...
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St. Louis, MO
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Baltimore, Maryland 21228
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Baltimore, MD
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Boston, MA
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Durham, North Carolina 27705
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Durham, NC
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Los Angeles, California 90073
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Los Angeles, CA
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722 W 168th St
New York, New York 10032
(212) 305-2500
Columbia Presbyterian Med Ctr On January 1, 1998, The New York Hospital publicly announced its...
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New York, NY
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