Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy.
| Status: | Archived |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | March 2008 |
| End Date: | March 2011 |
Extended Antibiotic Prophylaxis for the Prevention of Infectious Complications Associated With Tube Thoracostomy in Patients Undergoing Elective Thoracic Surgery: A Prospective, Randomized, Placebo-Controlled Trial
The purpose of this study is to evaluate if post-operative antibiotic prophylaxis decrease
infectious complications when compared to pre-operative antibiotics alone, in patients
undergoing elective thoracic surgery requiring tube thoracostomy (chest tube).
There is currently no evidence-based standard for the extended use of prophylactic
antibiotics in patients receiving thoracic surgery that results in the placement of a tube
thoracostomy (chest tube). The rationale for this prophylaxis is that antibiotics directed
at typical skin flora may reduce the rate of infectious complications, such as surgical site
infection and empyema.
Currently, clinicians' approach to post-operative antibiotic prophylaxis in patients
undergoing tube thoracostomy associated with thoracic and cardio-thoracic surgery varies
widely. While reducing the infectious complications of thoracic surgery is an important
goal, it is also important to reduce the use of unnecessary antibiotics. As there is
equipoise on the subject of extended antibiotic prophylaxis for tube thoracostomy, our study
will examine two prevailing clinical practices and attempt to determine if one leads to
better patient outcomes.
We found this trial at
1
site
850 Boylston Street
Chestnut Hill, Massachusetts 02467
Chestnut Hill, Massachusetts 02467
1-800-BWH-9999
Brigham & Women's Hospital Women's Health Center At Brigham and Women
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