Safety and Efficacy of TACLONEX Ointment in Adolescent Patients (Aged 12 to 17 Years) With Psoriasis Vulgaris



Status:Archived
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:July 2009
End Date:August 2011

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The purpose of this study is to evaluate the safety and efficacy of 4 weeks of TACLONEX
ointment in adolescent patients with psoriasis vulgaris.


TACLONEX ointment has marketing approval in many countries for the treatment of psoriasis
vulgaris in adults. No studies have been conducted in patients less than 18 years of age.
However, about 25% of affected individuals are diagnosed between 10 and 19 years of age,
hence psoriasis is also prevalent in the adolescent age group (12-17 years).

All patients will receive TACLONEX. To evaluate the safety of TACLONEX ointment, all
adverse events will be recorded. In addition, any systemic absorption of the active
components, betamethasone dipropionate and calcipotriene, will be evaluated by assessing
adrenal function (using CORTROSYNâ„¢ test) and calcium metabolism (by measuring serum calcium
and the urinary calcium:creatinine ratio), respectively.


We found this trial at
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725 West Granada Blvd
Ormond Beach, Florida 32174
386-898-0547
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201 East Huron Street
Chicago, Illinois 60611
(847) 491-3741
Northwestern University Northwestern is recognized both nationally and internationally for the quality of its educational...
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Arlington, Texas 76011
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Fremont, California 94538
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1400 NW 12th Ave
Miami, Florida 33136
(305) 689-5511
University of Miami Hospital The University of Miami changed the face of modern health care...
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Norfolk, Virginia 23507
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Norfolk, VA
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San Diego, California 92123
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Seattle, Washington 98101
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St. Louis, Missouri 63110
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St. Louis, MO
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