Trial of an Intratumoral Injections of INXN-3001 in Subjects With Stage III or IV Melanoma



Status:Archived
Conditions:Skin Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:April 2009
End Date:December 2011

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Phase 1b' Open Label, Single Arm, Multicenter Trial to Evaluate the Safety, Tolerance, Response Rate and Immunological Effects of Repeated Intratumoral Injections of Adenoviral Transduced Autologous Dendritic Cells Engineered to Express hIL-12(INXN-3001) in Response to an Oral Activator Ligand Administered in Intra-Patient Escalating Doses in Patients With Unresectable Stage III C or IV Malignant Melanoma


The purpose of this study is to test the safety of an investigational combination
drug/immunotherapy for the treatment of Stage III/IV melanoma.


This study will examine the effects of an oral Activator Ligand administration to modulate
the timing of gene expression of human IL-12 by adenovirus-transduced dendritic cells
injected into tumors.


We found this trial at
9
sites
Scottsdale, Arizona 85258
353
mi
from 91732
Scottsdale, AZ
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801 North 29th Street
Billings, Montana 59107
406-238-2500
Billings Clinic Based in Billings, Montana, Billings Clinic is a community-governed health care organization consisting...
949
mi
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Billings, MT
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1225
mi
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Dallas, TX
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1818
mi
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Goshen, IN
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Newark, Delaware 19713
2347
mi
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Newark, DE
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Orange, California 92868
21
mi
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Orange, CA
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Park Ridge, Illinois 60068
1720
mi
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Park Ridge, IL
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2121
mi
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Pittsburgh, PA
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Santa Monica, California 90404
26
mi
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Santa Monica, CA
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