The Effects of Linezolid and Vancomycin on Inflammation and Cellular Signaling Vents
| Status: | Archived |
|---|---|
| Conditions: | Hospital |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | January 2009 |
| End Date: | June 2010 |
We will determine if linezolid inhibits cellular activation and production of
pro-inflammatory cytokines, providing mechanistic rationale for its clinical efficacy and
the justification for further investigations in S. Aureus sepsis.
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