Primary Tumor Harvest for the Purpose of Possible Use in a Future Clinical Trial in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Cancer



Status:Active, not recruiting
Conditions:Ovarian Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:5/13/2018
Start Date:September 2008
End Date:December 2018

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Study of Primary Tumor Harvest for the Purpose of Possible Use in a Future Clinical Trial in Patients With Ovarian, Fallopian Tube or Primary Peritoneal Cancer (Ovarian Spore)

The purpose of this research study is to collect tumor samples at the time of surgery and
store them for possible use as part of an experimental vaccine study for the participants
cancer in the future.

- Even if tumor sample is collected, the participant is under no obligation to participate
in the vaccine study.

- Participants will have their regularly planned surgery as described by their surgeon.
During the surgery, tumor samples will be collected. We will only collect tumor that is
not needed and could otherwise be thrown away.

- The tumor samples will be frozen and placed in storage for up to two years.

Inclusion Criteria:

- Clinical suspicion of advanced ovarian, fallopian tube or primary peritoneal cancer as
determined by a gynecologic oncologist

- Patients are planning to undergo primary or secondary debulking surgery as part of
standard of care for their disease

- Estimated life expectancy of 6 months or greater

- 18 years of age or older

Exclusion Criteria:

- More than one prior chemotherapy regimen

- Serious intercurrent illness such as infection requiring IV antibiotics, or
significant cardiac disease characterized by significant arrhythmia, unstable ischemic
coronary disease or congestive heart failure

- Known HIV infection

- Active second malignancy, aside from basal cell or squamous cell carcinoma of the skin

- Significant autoimmune disease, including psoriasis

- History of clinically significant venous thromboembolism
We found this trial at
4
sites
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
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Boston, MA
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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Boston, MA
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75 Francis street
Boston, Massachusetts 02115
(617) 732-5500
Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Boston, MA
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450 Brookline Ave
Boston, Massachusetts 2215
617-632-3000
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Boston, MA
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