Psychiatric Genotype/Phenotype Project Repository



Status:Archived
Conditions:Depression, Major Depression Disorder (MDD), Psychiatric, Bipolar Disorder
Therapuetic Areas:Psychiatry / Psychology, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:September 2008

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Psychiatric Genotype/Phenotype Project


The purpose of this project is to obtain DNA, brain imaging data, other biological samples
(e.g., urine, serum), and a comprehensive clinical assessment on patients with schizophrenia
and other psychotic disorders, bipolar disorder, major depression, and normal volunteer
controls. Understanding the physical and genetic factors related to these disorders will
help us make progress in fitting treatments to an individual's needs. Participants will
take part in a detailed clinical assessment, two blood draws, and an MRI scan over two
visits. Participants will also be asked to provide urine and saliva samples.


The links between psychiatric symptoms and underlying biological processes remain unclear at
this time. Unipolar Major Depressive Disorder, Bipolar Disorder, and Schizophrenia are
associated with major disruptions in functioning and quality of life. Understanding the
causal physiological and genetic factors involved in each of these disorders would allow us
to make great strides in tailoring treatment to the individual's needs. Because the
etiology of these disorders are likely multifactorial in nature, a study examining a wide
range of variables might best allow us to examine the interactions between different factors
and to get a better sense of how genes and the brain interact to produce psychiatric
disorder.


We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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mi
from
Nashville, TN
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