A Study to Assess Whether PDE5 Inhibitors Increase the Chance of Triggering the Onset of Acute NAION



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:Any
Updated:10/21/2012
Start Date:November 2008
End Date:November 2012
Contact:Pfizer CT.gov Call Center
Phone:1-800-718-1021

Use our guide to learn which trials are right for you!

Case Crossover Study of PDE5 Inhibitor Exposure as a Potential "Trigger Factor" for Acute NAION


The objective of this non-interventional study is to examine whether use of
Phosphodiesterase Inhibitors (PDE5s), including use of sildenafil, vardenafil, or tadalafil,
triggers the onset of acute NAION.


Sites will identify patients who meet the entry criteria during the conduct of their normal
practice. Patients meeting these criteria will be offered participation in the study after
reading and completing an informed consent document.

Inclusion Criteria:

- Male aged ≥45 years;

- Experienced abrupt visual change in only 1 eye

Exclusion Criteria:

- Pain determined by an ophthalmologist to be consistent with an inflammatory/arteritic
process or optic neuritis;

- History of NAION or optic neuritis.

- Participation in other studies within 60 days prior to entry in the study.
We found this trial at
32
sites
Duluth, Minnesota 55805
1610
mi
from 91732
Duluth, MN
Click here to add this to my saved trials
235 East 42nd Street
Clifton, New Jersey 07013
2434
mi
from 91732
Clifton, NJ
Click here to add this to my saved trials
Akron, Ohio 44314
2038
mi
from 91732
Akron, OH
Click here to add this to my saved trials
Alabaster, Alabama 35007
1788
mi
from 91732
Alabaster, AL
Click here to add this to my saved trials
Alliance, Nebraska 69301
992
mi
from 91732
Alliance, NE
Click here to add this to my saved trials
Anchorage, Alaska 99501
2343
mi
from 91732
Anchorage, AK
Click here to add this to my saved trials
Anderson, South Carolina 29621
2009
mi
from 91732
Anderson, SC
Click here to add this to my saved trials
Arkansas City, Kansas 67005
1194
mi
from 91732
Arkansas City, KS
Click here to add this to my saved trials
Arvada, Colorado 80005
814
mi
from 91732
Arvada, CO
Click here to add this to my saved trials
Asheville, North Carolina 28801
2002
mi
from 91732
Asheville, NC
Click here to add this to my saved trials
Ashland, Oregon 97520
612
mi
from 91732
Ashland, OR
Click here to add this to my saved trials
Atlanta, Georgia 30309
1918
mi
from 91732
Atlanta, GA
Click here to add this to my saved trials
Atlantis, Florida 33462
2307
mi
from 91732
Atlantis, FL
Click here to add this to my saved trials
Baltimore, Maryland 21234
2305
mi
from 91732
Baltimore, MD
Click here to add this to my saved trials
Bloomingdale, Illinois 60108
1707
mi
from 91732
Bloomingdale, IL
Click here to add this to my saved trials
Bossier City, Louisiana 71111
1403
mi
from 91732
Bossier City, LA
Click here to add this to my saved trials
Boston, Massachusetts 02115
2578
mi
from 91732
Boston, MA
Click here to add this to my saved trials
Bridgeport, Connecticut 06606
2473
mi
from 91732
Bridgeport, CT
Click here to add this to my saved trials
Burke, Virginia 22015
2268
mi
from 91732
Burke, VA
Click here to add this to my saved trials
Cape Girardeau, Missouri 63703
1607
mi
from 91732
Cape Girardeau, MO
Click here to add this to my saved trials
Cedar Rapids, Iowa 52401
1527
mi
from 91732
Cedar Rapids, IA
Click here to add this to my saved trials
Detroit, Michigan 48202
1965
mi
from 91732
Detroit, MI
Click here to add this to my saved trials
Fayetteville, Arkansas 72703
1354
mi
from 91732
Fayetteville, AR
Click here to add this to my saved trials
Houston, Texas 77030
1357
mi
from 91732
Houston, TX
Click here to add this to my saved trials
Incline Village, Nevada 89451
373
mi
from 91732
Incline Village, NV
Click here to add this to my saved trials
Lebanon, New Hampshire 03756
2515
mi
from 91732
Lebanon, NH
Click here to add this to my saved trials
Los Angeles, California 90027
25
mi
from 91732
Los Angeles, CA
Click here to add this to my saved trials
Pittsburgh, Pennsylvania 15212
2118
mi
from 91732
Pittsburgh, PA
Click here to add this to my saved trials
Rochester, New York 14642
2242
mi
from 91732
Rochester, NY
Click here to add this to my saved trials
Seattle, Washington 98166
951
mi
from 91732
Seattle, WA
Click here to add this to my saved trials
Washington, District of Columbia 20003
2281
mi
from 91732
Washington,
Click here to add this to my saved trials
West Jordan, Utah 84088
559
mi
from 91732
West Jordan, UT
Click here to add this to my saved trials