Treatment Based on Molecular Profiling Diagnosis Carcinoma of Unknown Primary Site



Status:Archived
Conditions:Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:August 2008
End Date:August 2011

Use our guide to learn which trials are right for you!

A Phase II Study of Chemotherapy Treatment Based on Molecular Profiling Diagnosis for Patients With Carcinoma of Unknown Primary Site


This is a non-randomized Phase II study. Patients determined at initial diagnosis to have a
carcinoma of unknown primary site will have their treatment selected with the use of a
molecular profiling assay. A molecular profiling assay will be performed on
paraffin-embedded tumor tissue from a biopsy specimen. Patients given specific diagnoses
(e.g., lung, pancreas, colon, breast, renal cell, prostate and ovarian cancer) will receive
treatment regimens of proven activity. If no specific diagnosis is made with the molecular
profiling assay, empiric chemotherapy with paclitaxel, carboplatin, bevacizumab and
erlotinib will be administered.


Patients in all subgroups will be evaluated for response to treatment after completing 2
cycles. Standard, disease specific, restaging methods will be employed. Patients with
objective response or stable disease will continue treatment, with subsequent re-evaluations
after every 2 cycles of therapy.


We found this trial at
20
sites
3840 Broadway
Fort Myers, Florida 33901
(239) 275-6400
?
mi
from
Fort Myers, FL
Click here to add this to my saved trials
Gainesville, Florida 30501
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
9143 Philips Hwy # 560
Jacksonville Beach, Florida 32250
?
mi
from
Jacksonville Beach, FL
Click here to add this to my saved trials
1730
Lakeland, Florida 33805
?
mi
from
Lakeland, FL
Click here to add this to my saved trials
2501 N Orange Ave # 235
Orlando, Florida 32804
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Baton Rouge, Louisiana 70806
?
mi
from
Baton Rouge, LA
Click here to add this to my saved trials
6410 Rockledge Dr #660
Bethesda, Maryland 20817
(301) 571-0019
Center for Cancer & Blood Disorders Widely recognized for its compassionate, expert care, the Center...
?
mi
from
Bethesda, MD
Click here to add this to my saved trials
Chattanooga, Tennessee 37404
?
mi
from
Chattanooga, TN
Click here to add this to my saved trials
5053 Wooster Rd
Cincinnati, Ohio 45226
(513) 751-2273
Oncology Hematology Care Our more than 60 physicians and advanced practice providers throughout neighborhood offices...
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
?
mi
from
Evansville, IN
Click here to add this to my saved trials
Grand Rapids, Michigan 49503
?
mi
from
Grand Rapids, MI
Click here to add this to my saved trials
Huntsville, Alabama 35805
?
mi
from
Huntsville, AL
Click here to add this to my saved trials
Jackson, Mississippi 39202
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Louisville, Kentucky 40207
?
mi
from
Louisville, KY
Click here to add this to my saved trials
Marietta, Georgia 30060
?
mi
from
Marietta, GA
Click here to add this to my saved trials
Morristown, New Jersey 07960
?
mi
from
Morristown, NJ
Click here to add this to my saved trials
250 25th Ave N, Ste 100
Nashville, Tennessee 37023
615-320-5090
Tennessee Oncology, PLLC Since 1976 Tennessee Oncology has been providing quality cancer care. In 2013,...
?
mi
from
Nashville, TN
Click here to add this to my saved trials
8303 Dodge Street
Omaha, Nebraska 68114
(402) 354–4000
Nebraska Methodist Hospital Methodist Hospital is a general medical and surgical hospital in Omaha, NE....
?
mi
from
Omaha, NE
Click here to add this to my saved trials
Richmond, Virginia 23235
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Spartanburg, South Carolina 29303
?
mi
from
Spartanburg, SC
Click here to add this to my saved trials