UC Health University of Cincinnati Physicians
MLC 7004%2c 3333 Burnet Avenue
Cincinnati, Ohio 45229
513-636-9223 http://healthnews.uc.edu/clinicaltrials/ matig@ucphysicians.com

Use our guide to learn which trials are right for you!

Thank you for your interest in the Clinical Trials Office of UC Health University of Cincinnati Physicians. University of Cincinnati Physicians has a close partnership with the University of Cincinnati (UC) Academic Health Center, with members serving as faculty of and conducting clinical research at the UC College of Medicine. Clinicians at University of Cincinnati Physicians routinely conduct industry, investigator-initiated and National Institutes of Health (NIH) sponsored clinical studies (Phase I -IV), conforming to all regulatory requirements in an efficient and fiscally sound manner.

About University of Cincinnati Physicians

University of Cincinnati Physicians is the clinical practice management group for about 650 University of Cincinnati College of Medicine faculty working in more than 25 different medical specialties, including:

  • Anesthesiology
  • Dermatology
  • Emergency Medicine
  • Family Medicine
  • Imaging Centers
  • Internal Medicine
  • Neurology
  • Neurosurgery
  • OB/GYN
  • Occupational and Environmental Medicine
  • Ophthalmology
  • Orthopedic Surgery
  • Otolaryngology
  • Pathology
  • Physical Medicine and Rehabilitation
  • Primary Care
  • Psychiatry
  • Radiation Oncology
  • Radiology
  • Surgery

As part of its mission to be a leader in improving health, University of Cincinnati Physicians also routinely conducts research that improves the quality of care in the community, the nation and the world.

Our investigators have experience in more than 200 therapeutic areas, including:

  • AIDS-Antiretroviral Therapy
  • Ablation Therapy
  • Abnormal Blood Count
  • Acidosis
  • Acne
  • Acoustic Neuroma
  • Acquired Immune Deficiency
  • Actinic Keratosis
  • Acute Coronary Syndromes
  • Adrenal Gland Malignancies
  • Adult Respiratory Distress Syndrome
  • Airway Management
  • Alcohol and Drug Dependence
  • Alcohol Septal Ablations for HOCM ASD/PFO Closures
  • Allergenic Potential of Microbial Pesticides
  • Alzheimer's Disease
  • Androgenetic Alopecia
  • Anemia
  • Anemia (Post-Partum)
  • Anemia in Chronic Renal Failure
  • Aneurism- ruptured, unruptured, reoccurring
  • Anorexia Nervosa
  • Anticoagulant Therapy
  • Anxiety Disorders
  • Asthma
  • Atopic Dermatitis
  • Atopic Dermatitis (Pediatric)
  • Atrial Fibrillation
  • Attention Deficit Disorder
  • Attention Defecit Hyperactivity Disorder
  • Autoimmune Hepatitis
  • Bacterial Infections
  • Bipolar Disorder (Pediatric, Adult)
  • Bladder Malignancies
  • Bone Growth Factors
  • Bone Metabolism
  • Bowel Disorders
  • Brain Depolarizations
  • Brain Tumors
  • Breast Cancer
  • Bulimia
  • Calciphylaxi
  • Cardiac Arrhythmias
  • Cardiac Device Therapy
  • Cardiac Diagnostic Imaging
  • Cardiomyopathies
  • Cardiovascular Disease Prevention
  • Carotid Artery Occlusions
  • Carotid Atherosclerosis
  • Cerebrovascular Hemorrhage
  • Cervical Cancer
  • Cervical Intrepithelial Neoplasia
  • Chemotherapy
  • Child and Adolescent Mental Health Disorders
  • Cholangiocarcinoma
  • Chronic Bronchitis
  • Chronic Kidney Disease
  • Chronic Obstructive Pulmonary Disease
  • Coagulation Defects
  • Colon Malignancies
  • Contact Dermatitis
  • Contact Dermatitis (Pediatric)
  • Contraception
  • Contraceptives
  • Coronary Interventions
  • Critical Care Medicine
  • Cutaneous Fragility
  • Cystic Fibrosis
  • Deep Brain Stimulation
  • Deep Venous Thrombosis
  • Degenerative Disc Disease
  • Dementia
  • Depressive Disorders
  • Diabetes Mellitus
  • Diagnostics
  • Dialysis
  • Diarrhea
  • Dysfunctional Uterine Bleeding
  • Dyslipidemia
  • Dysmenorrhea
  • Eating Disorders
  • Echocardiography
  • End Stage Renal Disease/Anemia
  • Endocrinologic System Malignancies
  • Endometrial Cancer
  • Endometriosis
  • Endoscopic Retrograde Cholangiopancreatography
  • Epilepsy
  • Esophageal Cancer
  • Female Infertility
  • Female Reproductive System Infections
  • Female Sexual Dysfunction
  • Fibromyalgia
  • Fungal Infections
  • Gastroesophageal Reflux Disease
  • Gastrointestinal Endoscopic Procedures
  • Gastrointestinal System Infections
  • Gastrointestinal System Malignancies
  • Geriatric Cognitive Impairment
  • HIV-Early Detection
  • HIV Complications
  • HIV Infection
  • HIV Prevention
  • HIV Testing
  • HPV Assay
  • Hand Dermatitis
  • Head & Neck Malignancies
  • Headaches
  • Heart Failure
  • Heart Transplantation
  • Hematologic System Malignancies
  • Hemophilia
  • Hepatobiliary Contrast Agents
  • Hormone Replacement Therapy
  • Hot Flashes
  • Huntington's Disease
  • Hyperlipidemia
  • Hyperphosphatemia
  • Hypertension
  • Ichtyosis
  • Idiopathic Pulmonary Fibrosis
  • Immunosuppression (Transplant)
  • In Vetro Fertilization
  • Infection in Immunocompromised Patients
  • Inflammatory Bowel Diseases
  • Inflammatory Disease
  • Interstitial Lung Disease
  • Intracerebral Hemorrhage
  • Intracranial Stenosis
  • Intraventricular Hemorrhage
  • Irritable Bowel Syndrome
  • Kidney Cancer
  • Kidney Disorders
  • Kidney Transplantation
  • Labor Induction
  • Leukemia
  • Leukopenia
  • Liver Cancer
  • Liver Disorders
  • Liver Transplantation
  • Low LibidoLung Cancer
  • Lymphomas
  • Malabsorption
  • Mechanical Ventiliation
  • Melanoma
  • Migraine Headaches
  • Movement Disorders
  • Multiple Myeloma
  • Mycosis Fungoides
  • Myelodysplastic Syndrome
  • Neurovascular Emergencies
  • Nicotine Addiction
  • Nuclear Magnetic Resonance Spectroscopy
  • Obesity
  • Obsessive-Compulsive Disorder
  • Occupational Immunologic Lung Diseases
  • Oncology- Phase I
  • Onychomycosis
  • Opportunistic Infections (HIV-Related)
  • Osteoarthritis
  • Osteomyelitis
  • Osteopenia
  • Osteoporosis
  • Ovarian Cancer
  • Overactive Bladder
  • Pancreatic Cancer
  • Pancreatic Transplantation
  • Pancreatic-Biliary Disease
  • Pancreatitis
  • Panic Disorders
  • Pap Collection Device
  • Parkinson's Disease
  • Peripheral Vascular Disease
  • Photoaging
  • Plasma Banking
  • Pleural Effusion
  • Pneumonia
  • Point of Care Testing
  • Polycystic Kidney Disease
  • Polycystic Ovary Syndrome
  • Pre-Hospital Care
  • Preeclampsia/Eclampsia
  • Premenstrual Syndrome
  • Preterm Labor
  • Prostate Malignancies
  • Pruritus
  • Psoriasis
  • Psychosis
  • Pulmonary Embolism
  • Pulmonary Rehabilitation
  • Renal Cancer
  • Renal Hypertension
  • Renal Transplant
  • Respiratory Failure
  • Respiratory System Infections (Upper & Lower)
  • Rheumatoid Arthritis
  • Rhinitis
  • Rosacea
  • Sarcoidosis
  • Sarcoma
  • Schizophrenia & Related Psychotic Disorders
  • Scleroderma
  • Seborrheic Dermatitis
  • Secondary Hyperparathyroidism
  • Septicemia/Septic Shock
  • Serum Banking
  • Sexual Dysfunction
  • Sickle Cell Anemia
  • Sleep Disorders/Sleep Apnea
  • Small Bowel Transplantation
  • Smoking Cessation
  • Solid Organ Transplantation in HIV-Infected
  • Spinal Cord Injury
  • Spinal Cord Stimulation
  • Steatohepatitis
  • Stroke
  • Subarachnoid Hemorrhage
  • Sun Damage
  • Systemic Lupus Erythematosus
  • Systemic Seminal Plasma Hypersensitivity Reactions
  • Testicular Cancer
  • Thalassemia
  • Thrombosis
  • Thyroid Malignancies
  • Tinea Pedis
  • Tissue Collection
  • Toxicology
  • Transonics
  • Transplantation (Organs)
  • Trauma
  • Traumatic Brain Injury
  • Ultrasound Contrast
  • Urinary System Malignancies
  • Uterine Leiomyomata
  • Vaginal Atrophy
  • Vascular Calcification
  • Vasomotor Symptoms
  • Vasospasm, Cerebral
  • Venous Access
  • Venous Thrombolysis
  • Viral Hepatitis
  • Vitamin D Metabolism
  • Xerosis

Michael Spigarelli, MD, PhD, medical director
Phone: (513) 636-3232
Email: michael.spigarelli@ucphysicians.com

Melinda Muenich, RN, MBA, business director
Phone: (513) 636-7130
Email: melinda.muenich@ucphysicians.com

Jacob Matig, marketing and recruiting coordinator
Phone: (513) 636-9223
Email: jacob.matig@ucphysicians.com

Cardiology/Vascular Diseases
Dental/Maxillofacial Surgery
Dermatology/Plastic Surgery
Immunology/Infectious Diseases
Pulmonary/Respiratory Diseases
Trauma/Emergency Medicine

About the University of Cincinnati Academic Health Center

The University of Cincinnati Academic Health Center houses some the university's most innovative and captivating science and research laboratories, including the colleges of Allied Health Sciences, Medicine, Nursing, and Pharmacy, and a number of patient care facilities and resources.

The UC Academic Health Center has played an important role in the University of Cincinnati's classification as a "very high" research university by the Carnegie Commission and consistent ranking as one of America's top public research universities for expenditures according to the National Science Foundation. In fiscal year 2009, the UC Academic Health Center and its affiliates received more $278 million in research funding (74 percent of UC's total funding), including:

  • $105.2 million in NIH research grant funding
  • $32.9 million in Department of Education research grant funding
  • $12.5 million in industry research grants and contracts

Historical achievements by UC researchers include the definitive study of the health effects of lead in children and the development of the popular antihistamine Benadryl. More recently, UC researchers were responsible for the development of a treatment to reduce brain damage in stroke patients. Through its affiliation with Cincinnati Children's Hospital Medical Center, the university also played an important role in the development of the first live, attenuated polio vaccine and the first functional heart-lung machine.

In April 2009, the National Institutes of Health (NIH) awarded the UC Academic Health Center and its affiliates an institutional Clinical and Translational Science Award (CTSA). The CTSA program supports a national consortium of medical research institutions designed to transform how biomedical research is conducted. Its goals are to speed the translation of laboratory discoveries into treatments for patients, to engage communities in clinical research efforts, and to train a new generation of clinical and translational researchers.

Partners and Affiliates

The UC Academic Health Center prides itself with excellent patient care and research programs, and strong affiliations with local hospitals throughout Greater Cincinnati. Below are some of our key program and affiliates.

  • UC Health University of Cincinnati Physicians
    University of Cincinnati Physicians is the clinical practice management group for UC College of Medicine faculty working in more than 25 different medical specialties.
  • Hoxworth Blood Center
    Hoxworth Blood Center collects, tests, processes and distributes blood and its components to 27 hospitals and medical centers in a 17-county area of Ohio, Kentucky and Indiana. The center is the only blood bank serving Greater Cincinnati.
  • Metabolic Diseases Institute
    The Metabolic Diseases Institute (formerly the Genome Research Institute) was created in 2001 to foster excellence in biomedical research—from basic science to translational medicine—and facilitate collaboration among academic and industrial researchers. Work at the Metabolic Diseases Institute is primarily focused on understanding the causes of disease and developing treatments for diabetes, obesity, cancer and cardiovascular diseases.
  • UC Barrett Cancer Institute at University Hospital
    The UC Barrett Cancer Institute at University Hospital is a research-based but patient care-oriented program that encompasses scientists and physicians from multiple disciplines and medical specialties. UC scientists evaluate and apply the latest medical advances, quickly translating scientific findings into practical patient care.
  • UC Neuroscience Institute
    A collaboration between UC's College of Medicine and University Hospital, this regional center encompasses nine neuroscience specialties dedicated to patient care, research, education and the development of new medical technologies related to stroke, tumors, epilepsy, and movement and sensory disorders.
  • UC Health University Hospital
    University Hospital is the official teaching hospital for UC's College of Medicine. Managed by the Health Alliance, University Hospital has the region's first and only verified Level I trauma center for adults.
  • Cincinnati Children's Hospital Medical Center
    Cincinnati Children's Hospital Medical Center is an international leader in research and medical care related to infant, child and adolescent diseases. The hospital is a major teaching affiliate for UC's College of Medicine.
  • Cincinnati Department of Veterans Affairs Medical Center
    The Cincinnati Department of Veterans Affairs Medical Center provides surgical, medical and psychiatric services to eligible veterans in the Tristate region. The hospital is a key surgical referral center for central Ohio and a primary teaching affiliate for UC's College of Medicine.
  • Shriners Hospitals for Children–Cincinnati
    One of four pediatric burn hospitals in North America, Shriners Hospitals for Children–Cincinnati specializes in complete care and reconstruction services—free of charge—for children who have suffered major burn injuries. The hospital is a teaching and research affiliate for UC's College of Medicine.
  • Christ Hospital
    Christ Hospital is a 555-bed primary care hospital and serves as a major teaching affiliate for UC's College of Medicine and practice site for several University of Cincinnati Physicians groups.
  • Jewish Hospital
    Jewish Hospital, a 200-bed hospital in suburban Cincinnati that serves as an affiliate teaching hospital for UC's College of Medicine.
  • Holmes Building
    The Holmes Building is the home of the University Health Services East Campus Clinic. The Holmes Building houses the departments of Athletic Medicine, Student Health Insurance, Immunizations, and includes a pharmacy. The Clinic's services are available to UC students with UC student health insurance or other forms of insurance and employees with occupational health issues.

Clinical Trials Office

The Clinical Trials Office of University of Cincinnati Physicians provides clinical investigators and sponsors with comprehensive support services, research tools, personnel and facilities to conduct or facilitate adult clinical research studies (as well as some select pediatric studies in collaboration with Cincinnati Children's Hospital Medical Center).


  • Marketing and business development
  • Study design and protocol development
  • Study placement
  • Contract and budget
  • Participant recruitment

Jacob Matig
Marketing and Recruiting Coordinator
UC Health University of Cincinnati Physicians
Clinical Trials Office
MLC 7004, 3333 Burnet Avenue
Cincinnati, OH 45229-3039
Cincinnati, OH 45229-3039
513-636-0168 (fax)

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