NCCR has been involved in clinical research since 1986. We focus on phase I, II, III, and IV research. We conduct research in the following areas:

• Arthritis
• Cardiovascular diseases
• Dermatology
• Devices--General
• Gastrointestinal diseases
• Gynecology
• Infectious diseases/Anti-infectives
• Label Comprehension and Actual use studies
• Neurology
• Ophthalmology
• Otolaryngology
• Pain Management
• Pediatrics
• Respiratory diseases
• Rx to OTC studies
• Pharmacoeconomic Studies
• Cost Effectiveness Analysis
• Quality of Life Studies
• Urology

We have worked previously with the following sponsors: Abbott, Alcon, Alkermes, Alza Pharmaceuticals, Ascent Pediatrics, Astra Merck, Astra USA, Aventis, Baker Norton, Bayer, Boehringer Ingelheim, Bristol-Myers Squibb, Ciba Geigy, Dey Laboratories, Dura, Ethical, Fisons, Forest, G.D.Searle, Genentech, Glaxo SmithKline, Hajuku, Hoffman LaRoche, Janssen, J&J Merck, Marion Merrell Dow, McNeil Consumer, Merck, Miles, Muro, Novartis, Organon, Pfizer, Pharmacia & Upjohn ,Pozen, Procter & Gamble, Purdue Pharma,Rhone-Poulenc Rorer, A. H. Robins, R. W. Johnson, Sankyo, Sanofi Winthrop, Schering-Plough, Sepracor,SmithKline Beecham, Solvay, Syntex, Tap Pharmaceuticals, UCB Pharma, ViroPharma, Wallace Laboratories, Warner-Lambert,Whitehall Laboratories, Whitehall, Wyeth-Ayerst, and Zeneca.

Craig LaForce, M.D., Karen Dunn, M.D., or Alan Aarons, M.D. serve as the principal investigator for the majority of our studies. NCCR also works with a group of physicians with a variety of backgrounds and specialties.

Dr. LaForce is Board Certified in Allergy/Immunology and Pediatrics with extensive experience conducting clinical trials. Dr. LaForce has been in private practice since 1980 and conducting clinical trials since 1986. During the period 1981-1982, he was also the Director of the Pediatric Allergy Clinic at the University of North Carolina at Chapel Hill. Dr. LaForce completed medical School at Jefferson Medical College in Philadelphia. He completed his residency at the University of North Carolina at Chapel Hill and Postdoctoral Fellowship (Pediatric/Adult Allergy and Immunology) at National Jewish Hospital, Denver, CO.

Dr. Dunn is also Board Certified in Allergy/Immunology and Pediatrics. Dr. Dunn completed medical school at New York Medical School. She completed her residency at St. Christopher's Hospital for Children, Philadelphia, PA and Postdoctoral Fellowship (Immunology and Allergy) at the UCLA School of Medicine. She has been in private practice and conducting clinical trials since 1988. Prior to going into private practice, Dr. Dunn was Co-Director of the Cystic Fibrosis Center at the UCLA School of Medicine.

Dr. Aarons is Board Certified in Internal Medicine and Allergy/Immunology. He completed medical school at the University of Maryland, residency (Internal Medicine) at the University of North Carolina at Chapel Hill, and Postdoctoral Fellowship (Allergy/Immunology) at National Jewish Hospital, Denver, CO.

The following is a list of additional investigators for our studies:

• Benton Satterfield, M.D. -- Obstetrics/Gynecology
• Mitch Collman, M.D. -- Cardiology
• Beth Friedland, M.D. -- Ophthalmology

Patti Becherer has been the Clinical Research Manager at NCCR since 1989. She has a B.S. in Nursing and is a Certified Clinical Research Coordinator. Ms. Becherer has been involved with clinical trials since 1986. As Clinical Research Manager, Ms. Becherer is responsible for overseeing all aspects of clinical trials at NCCR.

Supporting the principal investigator in the completion of each study is a clinical research staff of more than a dozen professionals. Our Clinical Research Coordinators are responsible for the day-to-day progress of each study. Our CRC's are all trained professionals with a Bachelor's degree or higher, including two registered Nurses and 3 CCRCs.

Our administrative staff include a Regulatory Affairs Administrator whose responsibility it is to prepare and track filings to the IRB and other regulatory documents for each study.

We have access to a metropolitan population exceeding one million. We are also located next to three major universities (Duke, UNC-Chapel Hill, and North Carolina State).

Cardiology/Vascular Diseases
Dental/Maxillofacial Surgery
Dermatology/Plastic Surgery
Gastroenterology
Immunology/Infectious Diseases
Musculoskeletal
Nephrology/Urology
Neurology
Obstetrics/Gynecology
Ophthalmology
Otolaryngology
Pediatrics/Neonatology
Pharmacology/Toxicology
Pulmonary/Respiratory Diseases