Evaluation of Sickle Cell Liver Disease

Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)

Genetic, Brain Structure, and Environmental Effects on ADHD

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

Environmental Risk Factors for Myositis in Military Personnel

Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders

The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)

Tooth and Tissue Sample Collection During Wisdom Teeth Removal

Rapid Autopsy and Procurement of Cancer Tissue

Cerebrospinal Fluid Collection and Repository Storage

Evaluating New Radiation Techniques for Cardiovascular Imaging

Eltrombopag With Standard Immunosuppression for Severe Aplastic Anemia

Normal Values in Hearing and Balance Testing

Validating Pain Scales in Children and Young Adults

A Natural History Study of Patients With GNE Myopathy

Tocilizumab for KSHV-Associated Multicentric Castleman Disease

Clinical and Genetic Studies of Li-Fraumeni Syndrome

Neuropsychological Changes in Patients Receiving Radiation Therapy for Brain Metastases

Hormonal Regulation of Puberty and Fertility

Deep Brain Stimulation Surgery for Movement Disorders

PET Imaging and Lymph Node Assessment of IRIS in People With AIDS

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)

Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive

Deep Brain Stimulation Therapy in Movement Disorders

The Focal Electro-Oculogram in Macular Disease

Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products

Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

Genes Involved in Lipid Disorders

Characterization of Diseases With Salivary Gland Involvement

Trial of the Combination of Bortezomib and Clofarabine in Adults With Relapsed Solid Tumors

Gene Therapy Follow-up Protocol for People Previously Enrolled in NCI Experimental Transplantation and Immunology Branch Studies

Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody MEDI4736 in Combination With Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Cancers

Effect of Exercise Training on Physical, Cognitive, and Behavioral Function in People With TBI

Natural History, Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease

A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy

Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence

Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration

Evaluation of MiSeq for Microbial Identification in Specimens

Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

A Prospective Randomized and Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy

Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain

Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy

Clinical and Laboratory Analysis of Familial Cancer

Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME Study)

Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment With Transarterial Embolization (TAE) Alone or Combined With Thermal Ablation

Cholinergic Receptor Imaging in Dystonia

Screening for Alpha Thalassemia in Healthy Volunteers

Biospecimen Procurement for Experimental Transplantation and Immunology Branch Immunotherapy Protocols

Evaluation of Patients With Thyroid Disorders

Treatment of Patients With Cysticercosis With Praziquantel or Albendazole

Resistance to Vitamin D or Parathyroid Hormone

Inflammatory Responses in Normal Volunteers and Patients With Abnormal Immune Responses

Diagnosing and Treating Low Blood Sugar Levels

Apheresis to Obtain Plasma or White Blood Cells for Laboratory Studies

Diagnosis and History Study of Patients With Different Neurological Conditions

Evaluation, Treatment, and Training for Patients With Blood Disorders

Study of Proteus Syndrome and Related Congenital Disorders

Clinical and Basic Investigations Into Hermansky-Pudlak Syndrome

Genetic Study of Schizophrenia

Investigation of the Human Immune Response in Normal Subjects and Patients With Disorders of the Immune System and Cancer

Magnetic Resonance Imaging (MRI) Ofl Volunteers

Evaluation of Patients With HAM/TSP

Evaluation of Patients With Liver Disease

Genetic Studies of Insulin and Diabetes

Diagnosis of Pheochromocytoma

Study of Adrenal Gland Tumors

Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

Study of Arthritis and Related Conditions

Clinical Trial of Fluoxetine in Anxiety and Depression in Children, and Associated Brain Changes

Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers

Stem Cell Collection for Adult Volunteers

Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Primary and Chronic HIV-Infected Patients

Study of Factors Regulating Mast Cell Proliferation

Study of Inborn Errors of Cholesterol Synthesis and Related Disorders

Genetic Basis of Immunodeficiency

Evaluation and Treatment of Neurosurgical Disorders

Investigating the Use of Quercetin on Glucose Absorption in Obesity, and Obesity With Type 2 Diabetes

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

Natural History of Sickle Cell Disease

Mutations in Genes Associated With Pentalogy of Cantrell

Progression of Spinal Fusion in Ankylosing Spondylitis

Use of Tracking Devices to Locate Abnormalities During Invasive Procedures

Training for Diagnosing Neurological Disorders

Use of Cysteamine in the Treatment of Cystinosis

Physical and Behavioral Traits of Overweight and Obese Adults

Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus

Follow-Up Study of Subjects Previously Enrolled in Poxviral Vector Gene Transfer Studies