Southern California Permanente Medical Group (SCPMG) Clinical Trials Research Program (CTRP) focuses on advancing the practice of medical care to improve health outcomes. Clinical trials investigators are practicing physicians who bridge the gap between research and clinical practice. Typically, research in Kaiser Permanente is aimed at evaluating the impact at the bedside and using this perspective to develop study designs that answer clinically releveant questions. Study participants are recruited from within the Kaiser Foundation Health Plan's 3.1 million Southern California members.
Kaiser Permanente (KP) is the largest vertically integrated private health care delivery system in the United States. Research is important to Kaiser Permanente because it is not only a part of our organizational mission, but it provides Kaiser Permanente Health Plan members access to innovative new technologies and medicines.
Within the Department of Research and Evaluation, the Clinical Trials Research office Program is a Kaiser Southern California regional resource which coordinates all aspects of clinical trials services, interface between investigators, sponsors, and regulatory bodies. Sponsors will be directed to appropriate investigators for clinical trials. Once an investigator is identified, we work with the sponsor and the investigator to facilitate their application through IRB, finance, and contracting. We also hire and provide study coordinators and research associates to implement clinical trials studies.
In Southern California, over 5,500 physicians take care of over 3.3 million members in fourteen geographic areas. With this resource, CTRP is capable of conducting any clinical research project, from the smallest pilot studies to drug trials to outcomes and quality of life analyses. Our experience stretches from Phase II to Phase IV and beyond, encompassing post-marketing analyses. CTRP conducts studies in more than 26 therapeutic areas: Allergy, Bio-chemotherapy, Cardiac surgery, Cardiology, Endocrinology, Gastroenterology, Gynecology oncology, Hepatology, Infections diseases, Internal medicine, Nephrology, Metabolic genetics, Neurology, Adult oncology, Pain Management, Pediatric oncology, Ophthalmology, Plastic surgery, Surgical oncology, Urology, Pediatrics, and Vascular surgery.
Clinical trials investigators are all practicing physicians in a variety of specialties, incorporating state-of-the-art research to their own practices. Their informed input on study design and interpretation creates more efficient, practical, and pertinent research. Clinical trials investigators also focus strongly on disseminating research results, publishing more than 300 articles per year in peer-reviewed journals. These studies have advanced medical care, improved health outcomes and impacted medical practice internationally.
CTRP staff has experience with all aspects of clinical trials management: site management, human subject protection, budget development, and contracting. CTRP provides support for regulatory processes, filing and maintenance of investigator-initiated INDs/IDEs, protocol review, new project consultation, and training. CTRP also provides site management and clinical monitoring capabilities for some of our investigators. Services provided include: qualification /selection and site recruitment, investigative site start-up and training, clinical trial enrollment, site regulatory compliance, CRF completion, data collection, initial staff contacts and query resolution.
The CTRP staff include: Valerie Crooks, DSW who provides administrative oversight of the program, sponsor protocol review, and identifies appropriate investigators and Cynthia A. Brown, Clinical Trials Research Manager.
Kaiser Permanente Southern California (KPSC) provides comprehensive health care on a pre-paid basis to 3.1 million residents of Southern California. The population served by the program is diverse and broadly representative of the population of Southern California ethnically and in terms of education and income.
Cardiology/Vascular Diseases
Dermatology/Plastic Surgery
Endocrinology
Gastroenterology
Hematology
Immunology/Infectious Diseases
Musculoskeletal
Nephrology/Urology
Neurology
Obstetrics/Gynecology
Oncology
Ophthalmology
Otolaryngology
Pediatrics/Neonatology
Psychiatry/Psychology
Pulmonary/Respiratory Diseases
Rheumatology
Trauma/Emergency Medicine
Southern California Permanente Medical Group (SCPMG) Clinical Trials Research Program (CTRP) research is conducted at all 13 strategically located Kaiser Permanente Medical Centers of Southern California: Baldwin Park, Bellflower, Fontana, Harbor City/South Bay, Irvine, Los Angeles, Ontario, Orange County, Panorama City, Riverside, San Diego, West Los Angeles, and Woodland Hills.
Daniel J. Pinion
Clinical Trials Research
Kaiser Permanente Southern California Clinical Trials
100 South Los Robles, 2nd Floor
Pasadena, CA 91101
USA
626-564-5667
626-564-7872 (fax)
Daniel.J.Pinion@kp.org
www.kp.org/scpct