Developing Viability Index for Machine Perfused Livers
| Status: | Recruiting |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 3/9/2019 |
| Start Date: | October 1, 2018 |
| End Date: | October 1, 2023 |
| Contact: | Heidi Yeh, MD |
| Email: | hyeh@mgh.harvard.edu |
| Phone: | 617-726-3664 |
Development of a Liver Viability Index for Transplantation
Machine perfusion technology is nearing the point of rescuing discarded liver grafts in the
hope of proving them to be or improving them to the point of being transplantable. However,
there are no validated metrics to determine transplantability after machine perfusion. This
study involves collecting biopsies from transplanted livers before and after implantation to
correlate metabolite and gene expression with post-transplant function. This data will help
develop a viability index for machine perfused livers.
hope of proving them to be or improving them to the point of being transplantable. However,
there are no validated metrics to determine transplantability after machine perfusion. This
study involves collecting biopsies from transplanted livers before and after implantation to
correlate metabolite and gene expression with post-transplant function. This data will help
develop a viability index for machine perfused livers.
Inclusion Criteria:
- Male or female 18-75 years of age.
- Candidate for a deceased-donor liver allograft.
Exclusion Criteria:
- Seropositivity for HIV-1.
We found this trial at
1
site
185 Cambridge Street
Boston, Massachusetts 02114
Boston, Massachusetts 02114
617-724-5200
Phone: 617-643-4087
Click here to add this to my saved trials
