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New Clinical Trials for Osteoarthritis (OA)

There is currently no cure for osteoarthritis. Treating osteoarthritis mainly deals with managing the symptoms of the disease. Over the last 20 years osteoarthritis clinical studies have focused on electrostimulation techniques. Unfortunately, no conclusive evidence has been found that these techniques work. Ongoing osteoarthritis clinical trials are being conducted to learn ways to better diagnose, treat and ultimately cure this painful and sometime debilitating disease.
 

What is Osteoarthritis (OA)?

Osteoarthritis (OA) occurs when the cartilage and bones in joints degrade to a point where they become painful, tender and stiff. It is also known as degenerative joint disease and degenerative arthritis. Osteoarthritis is the most common form of arthritis and it affects 27 million people in the U.S. It most often impacts weight-bearing joints like the hands, feet, spine, and hips. As a person ages the cartilage in their joints becomes less resilient. Lumps called Heberden’s nodes may form and while these are not more painful they can limit movement. Approximately 60% of the cases are linked to heredity, although mechanical issues can also cause osteoarthritis. Secondary causes include diabetes, congenital disorders and inflammatory diseases.
 

Osteoarthritis (OA) Treatments

Physical therapy and exercise have proven to be successful forms of treating osteoarthritis. They allow for better function, less pain and a delay in the onset of osteoarthritis. If a person is overweight they are encouraged to lose weight to take some of the pressure off of the joints that are being burdened. Medications that are prescribed for treating osteoarthritis include analgesics, acetaminophen and ibuprofen. Although these medications help with the pain they do not help make the osteoarthritis any better. In more extreme cases where the pain cannot be managed by physical therapy or medication joint replacement surgery may be performed.

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Showing 1-100 of 369
There are 369 Osteoarthritis (OA) Clinical Trials
Name City State Zip
Osteoarthritis (OA) Clinical Trial Birmingham AL 35216
Osteoarthritis (OA) Clinical Trial Birmingham AL 35216
Osteoarthritis (OA) Clinical Trial Port Orange FL 32129
Osteoarthritis (OA) Clinical Trial DeLand FL 32720
Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain Birmingham AL
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee Anniston AL 36207
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Alabaster AL 35007
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Alabaster AL 35007
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee Tucson AZ 85741
Augmentâ„¢ Injectable Bone Graft Compared to Autologous Bone Graft as a Bone Regeneration Device in Hindfoot Fusions Tucson AZ 85712
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Tucson AZ 85724
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Tucson AZ 85741
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Tucson AZ 85710
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Tempe AZ 85282
Uniglideâ„¢ Mobile Bearing Unicondylar Knee System vs the Uniglideâ„¢ Fixed Bearing Unicondylar Knee System Sun City West AZ 85375
Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty Sun City West AZ 85375
Study of the Use of Laser Light to Treat Osteoarthritis of the Hand. Phoenix AZ 85014
Post-Market Study of the 3DKneeâ„¢ System Peoria AZ
Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain Peoria AZ
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee Mesa AZ 85202
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Glendale AZ 85304
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Chandler AZ 85225
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Chandler AZ 85225
Safety and Effectiveness Study of Ascension's PyroCarbon Radial Head Compared to Ascension's Metal Radial Head Van Buren AR 72957
Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery Little Rock AR 72205
iUni Foundation Study Little Rock AR 72205
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Fayetteville AR 72703
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Fayetteville AR 72703
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee Westlake Village CA 91361
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Tustin CA 92780
Safety and Efficacy Study of Bee Venom to Treat Knee Osteoarthritis Tarzana CA 91356
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Stanford CA 94305
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Santa Rosa CA 95405
Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain Santa Clara CA 95051
Augmentâ„¢ Injectable Bone Graft Compared to Autologous Bone Graft as a Bone Regeneration Device in Hindfoot Fusions San Francisco CA 94115
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time San Fernando Valley CA 91505
Triathlon® PKR Outcomes Study San Diego CA 92120
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee San Diego CA 92108
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time San Diego CA 92108
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Sacramento CA 95817
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Paramount CA 90723
iUni Foundation Study Monterey CA 93940
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Los Angeles CA 90073
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Los Angeles CA 90073
Comparing Manipulation, Rehabilitation and Combination of the Two in the Treatment of Knee Osteoarthritis Los Angeles CA 90004
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Los Angeles CA 90036
Study of the Use of Laser Light to Treat Osteoarthritis of the Hand. Long Beach CA 90803
Comparison of a Metal Backed Fixed-Bearing Tibial Baseplate and an All-Polyethylene Tibia in Total Knee Arthroplasty Long Beach CA 90822
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Lomita CA 90717
Safety and Effectiveness Study of Ascension's PyroCarbon Radial Head Compared to Ascension's Metal Radial Head LaJolla CA 92037
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Laguna Hills CA 92653
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Laguna Hills CA 92637
Uniglideâ„¢ Mobile Bearing Unicondylar Knee System vs the Uniglideâ„¢ Fixed Bearing Unicondylar Knee System La Quinta CA 92253
iUni Foundation Study La Quinta CA 92253
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee La Mesa CA 91942
Post-Market Study of the 3DKneeâ„¢ System Fresno CA 93710
Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty Fresno CA 93710
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Fresno CA 93726
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Escondido CA 92025
Safety and Efficacy Study of Bee Venom to Treat Knee Osteoarthritis Encino CA 91316
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Chino CA 91710
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Burbank CA 91505
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Buena Park CA 90620
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Anaheim CA 92801
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Anaheim CA 92804
Gait Analysis of Anterior Versus Posterior Approach in Performance of Total Hip Arthroplasty Lone Tree CO 80124
Safety and Effectiveness Study of Ascension's PyroCarbon Radial Head Compared to Ascension's Metal Radial Head Fort Collins CO 80525
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee Denver CO 80218
Longterm Safety Study of BEMA Buprenorphine in Subjects With Chronic Pain Denver CO
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Denver CO 80239
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Arvada CO 80005
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Arvada CO 80005
Ultrasound (US)-Guided Versus Sham Ultrasound Corticosteroid (CS) Knee Injections West Haven CT 06516
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Milford CT 06460
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Darien CT 06820
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Darien CT 06820
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Bridgeport CT 06606
A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee Bridgeport CT 06606
Electrical Stimulation After Total Knee Arthroplasty Newark DE 19716
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen Lewes DE 19958
Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee Tamarac FL 33321
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Stuart FL 34996
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee South Miami FL 33143
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Sarasota FL 34238
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Sanford FL 32771
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Plantation FL 33317
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Plantation FL 33317
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Pinellas Park FL 33781
iUni Foundation Study Pensacola FL 32561
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Palm Harbor FL 34684
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Orlando FL 32806
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee Ocala FL 34471
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time Miami FL 33183
Triathlon® PKR Outcomes Study Jacksonville FL 32204
iUni Foundation Study Jacksonville FL 32204
Knee Arthroplasty Registry Jacksonville FL 32204
Total Hip Registry Jacksonville FL 32204
Clinical Orthopaedic Data Bank (Acute and Chronic) Gainesville FL 32607
Safety and Effectiveness Study of Ascension's PyroCarbon Radial Head Compared to Ascension's Metal Radial Head Gainesville FL 32610
Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee Gainesville FL 32607

Showing 1-100 of 369
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