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New Clinical Trials for Constipation

Constipation is a condition that is seen in both adults and children. Many children suffer from it at times during their life when their diet is changing drastically, such as going on solid foods for the first time. Although constipation clinical research shows that the majority of adult constipation can be treated in non-medical ways, it is still an important condition to research and study. We are always in search of new ways of preventing, managing and treating constipation.
 
Current constipation clinical trials are listed on this page. If you or someone you know suffers from constipation on a regular basis, you may be eligible to participate in one of these studies.
 

What is Constipation?

Constipation is a symptom of problems with bowel movements being difficult to pass. This is usually caused either by an obstruction in the intestines or rectum, or by what is called colonic slow transit. Colonic slow transit is slow movement of the bowels due to diet and hormones. Constipation is also known as costiveness, dyschezia and dysynergic defecation. Constipation also refers to infrequent bowel movements, the need to strain during bowel movements or feelings of incomplete bowel movements. Constipation can become chronic and this is known as irritable bowel syndrome.
 

Constipation Treatments

Constipation treatments include diet changes, laxatives, enemas, biofeedback, and surgery. Since constipation is often caused by a lack of fiber or fluids, eating more fiber and increasing fluids will often take care of the problem. A permanent change in diet can also usually prevent the constipation from returning. Laxatives are not encouraged for treating constipation since people can become dependent on them. Enemas can be helpful, but they only remove stool from the rectum. If all else fails, physical removal of the bowel movement by a physician may be necessary.

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There are 70 Constipation Clinical Trials
Name City State Zip
Constipation Clinical Trial Birmingham AL 35216
Constipation Clinical Trial Port Orange FL 32129
Constipation Clinical Trial DeLand FL 32720
Methylnaltrexone for Treatment of Opiate-Induced Constipation in the Intensive Care Unit Mobile AL 36685
Comparison of Lubiprostone and Placebo for the Relief of Constipation From Constipating Medications Mobile AL 36693
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Birmingham AL
Colonic Transit Time Validation Study Tucson AZ 85723
Intestinal Microecology in Chronic Constipation Scottsdale AZ 85259
Trial Comparing Neomycin to Rifaximin Plus Neomycin in the Treatment of Methane Positive Subjects With Constipation Predominant Irritable Bowel Syndrome (C-IBS) Scottsdale AZ 85259
Effect of TU 100 on Rectal Compliance, Rectal Sensation and Small Bowel and Colonic Transit in Females With Constipation Scottsdale AZ 85259
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Phoenix AZ
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Little Rock AR
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation San Diego CA
Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain Pasadena CA 91105
Colonic Transit Time Validation Study Los Angeles CA 90048
Trial Comparing Neomycin to Rifaximin Plus Neomycin in the Treatment of Methane Positive Subjects With Constipation Predominant Irritable Bowel Syndrome (C-IBS) Los Angeles CA 90048
The Effect of Lubiprostone on Patterns of Contractions in the Small Bowel in Female Patients With Constipation Irritable Bowel Syndrome (C-IBS) Los Angeles CA 90048
BLI801 Laxative in Constipated Adults Anaheim CA 92801
Amitiza in Constipation Associated With PD (Parkinson's Disease) Tampa FL 33612
Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain Orlando FL 32806
BLI801 Laxative in Constipated Adults New Smyrna Beach FL 32168
BLI801 Laxative in Constipated Adults Jupiter FL 33458
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Fort Lauderdale FL
The Effectiveness of Lubiprostone in Constipated Diabetics Decatur GA 30033
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Atlanta GA
The Effectiveness of Lubiprostone in Constipated Diabetics Atlanta GA 30322
Domperidone for Relief of Gastrointestinal Disorders Urbana IL 61801
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Evanston IL
Starch-entrapped Microspheres [Nutrabiotix Fiber] for Gut Health Chicago IL 60612
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Anderson IN
Colonic Transit Time Validation Study Iowa City IA 52242
Sierra High Definition Ano-Rectal Manometry Iowa City IA 52242
Investigation of Supra Fiber in the Treatment of Adults With Constipation Iowa City IA 52242
Rectal Sensory Training - A Study of Two Techniques Iowa City IA 52242
Mechanism of Action of Biofeedback Therapy Iowa City IA 52242
Effect of Lubiprostone on Methanogenesis and Bowel Function in Chronic Constipation. Iowa City IA 52242
Colonic Transit Time Validation Study Kansas City KA 66160
Evaluation of the Efficacy and Safety of ADL5945 Once Daily for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain New Orleans LA 70114
Medications Development for Drug Abuse Disorders Lutherville MD 21093
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Baltimore MD
Colonic Transit Time Validation Study Boston MA 02114
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Ayer MA
Colonic Transit Time Validation Study Kalamazoo MI 49007
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Detroit MI
Colonic Transit Time Validation Study Ann Arbor MI 48109
Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation Ann Arbor MI 48109
Colonic Transit Time Validation Study Rochester MN
Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients Rochester MN 55905
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation St Louis MO
AcuGraph and Digestive Symptoms Chesterfield MO 63017
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Grand Island NE
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Teaneck NJ
Lubiprostone in Patients With Multiple Sclerosis Associated Constipation Rochester NY 14642
Colonic Transit Time Validation Study Buffalo NY 14215
Colonic Transit Time Validation Study Winston-Salem NC 27157
Dysfunctional Voiding and Lower Urinary Tract Symptoms With Baclofen Winston-Salem NC 27157
A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation in Subjects With Chronic, Non-Malignant Pain Raleigh NC 27612
Colonic Transit Time Validation Study Chapel Hill NC 27599
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Asheville NC
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Akron OH
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Bend OR
Colonic Transit Time Validation Study Philadelphia PA 19140
Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome Philadelphia PA 19107
Mechano-physiological Approach to Anorectal Function Hershey PA 17033
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Allentown PA
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Houston TX
Amitiza in Constipation Associated With PD (Parkinson's Disease) Houston TX 77030
Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation Salt Lake City UT
Methylnaltrexone for Opioid-induced Constipation in Cancer Patients Burlington VT 05401
A Colonic Tube to Improve Bowel Function in Spinal Cord Injury Milwaukee WI 53295
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