Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.



Status:Recruiting
Conditions:Obesity Weight Loss, Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - Any
Updated:3/27/2019
Start Date:March 1, 2019
End Date:April 10, 2020
Contact:Novo Nordisk
Email:clinicaltrials@novonordisk.com
Phone:(+1) 866-867-7178

Use our guide to learn which trials are right for you!

Investigation of Safety and Efficacy of NNC0174-0833 for Weight Management - a Dose Finding Trial.

This study will look at the change in body weight in people taking NNC0174-0833, liraglutide
and "dummy" medicine, from the start to the end of the study. As well as taking the medicine,
participants will have talks with study staff about healthy food choices, how to be more
physically active and what participants can do to lose weight. Participants will either take
NNC0174-0833, liraglutide or "dummy" medicine - which treatment participants get is decided
by chance. Participants will need to take one injection once a week or once a day, depending
on the treatment. The study medicine is injected with a thin needle in a skin fold in the
stomach, thigh or upper arm. The study will last for about 8 months. Participants will have
12 clinic visits with the study doctor.


Inclusion Criteria:

- 18 years or older at the time of signing the informed consent.

- Female subject of non-childbearing potential or Male subject who is surgically
sterilised (vasectomy) or who is willing to use adequate contraceptive methods (as
required by local regulation or practice) throughout the trial (until 'end of trial').

- BMI equal to 30.0 kg/m^2 or greater or BMI equal to 27.0 kg/m^2 or greater with the
presence of at least one of the following weight-related comorbidities (treated or
untreated): hypertension or dyslipidaemia (to be assessed at the investigator's
discretion).

Exclusion Criteria:

- HbA1c equal to 48 mmol/mol (6.5 percentage) or greater as measured by the central
laboratory at screening.

- A self-reported change in body weight greater than 5 kg (11 lbs) within 90 days prior
to screening irrespective of medical records.
We found this trial at
22
sites
Ponte Vedra, Florida 32081
?
mi
from
Ponte Vedra, FL
Click here to add this to my saved trials
Anaheim, California 92801
?
mi
from
Anaheim, CA
Click here to add this to my saved trials
Arlington, Virginia 22206
?
mi
from
Arlington, VA
Click here to add this to my saved trials
Bristol, Tennessee 37620
?
mi
from
Bristol, TN
Click here to add this to my saved trials
?
mi
from
Calgary,
Click here to add this to my saved trials
Chicago, Illinois 60612
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Crystal River, Florida 34429
?
mi
from
Crystal River, FL
Click here to add this to my saved trials
Elkridge, Maryland 21075
?
mi
from
Elkridge, MD
Click here to add this to my saved trials
Franklin, Ohio 45005
?
mi
from
Franklin, OH
Click here to add this to my saved trials
Gaffney, South Carolina 29341
?
mi
from
Gaffney, SC
Click here to add this to my saved trials
Greensboro, North Carolina 27408
?
mi
from
Greensboro, NC
Click here to add this to my saved trials
Jacksonville, Florida 32207
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
?
mi
from
Mason, OH
Click here to add this to my saved trials
Norman, Oklahoma 73069
?
mi
from
Norman, OK
Click here to add this to my saved trials
North Dartmouth, Massachusetts 02747
?
mi
from
North Dartmouth, MA
Click here to add this to my saved trials
Pembroke Pines, Florida 33026
?
mi
from
Pembroke Pines, FL
Click here to add this to my saved trials
Richmond, Virginia 23219
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Rochester, New York 14609
?
mi
from
Rochester, NY
Click here to add this to my saved trials
Round Rock, Texas 78681
?
mi
from
Round Rock, TX
Click here to add this to my saved trials
Spartanburg, South Carolina 29303
?
mi
from
Spartanburg, SC
Click here to add this to my saved trials
Spring Valley, California 91978
?
mi
from
Spring Valley, CA
Click here to add this to my saved trials
Wadsworth, Ohio 44281
?
mi
from
Wadsworth, OH
Click here to add this to my saved trials