Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup



Status:Recruiting
Conditions:Asthma, Infectious Disease
Therapuetic Areas:Immunology / Infectious Diseases, Pulmonary / Respiratory Diseases
Healthy:No
Age Range:1 - 7
Updated:12/27/2018
Start Date:October 23, 2018
End Date:April 30, 2019
Contact:Andrea Goettel, PharmD
Email:Andrea.Goettel@vumc.org
Phone:(615) 936-5495

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Trial Summary
Trial Overview
Inclusion Criteria

Comparison of Dexamethasone Oral Preparations to Assess Palatability and Adverse Effects in Children With Asthma and Croup

Study of the palatability and acceptability of dexamethasone oral tablets crushed and placed
in apple sauce or pudding in comparison with the IV solution mixed with sugar syrup and given
orally. It is hypothesized that dexamethasone tablets crushed and administered in apple sauce
or pudding will be more palatable and acceptable for pediatric patients receiving
dexamethasone for an acute asthma exacerbation or croup.


Inclusion Criteria:

- Diagnosis of acute asthma exacerbation or croup (laryngotracheitis) in the Vanderbilt
Children's Hospital Emergency Department

- Age 1 to 7 years

- Dexamethasone treatment indicated

- No other acute or chronic process accounting for signs and symptoms (e.g., foreign
body aspiration, pneumonia, cystic fibrosis)

- Have not received systemic corticosteroid for current episode prior to enrollment

Exclusion Criteria:

- Allergy to dexamethasone or apple sauce and pudding

- Unable to take medication orally
We found this trial at
1
site
Vanderbilt University Medical Center
1211 Medical Center Dr
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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Nashville, TN
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