An Investigational Immuno-therapy Study of Relatlimab Plus Nivolumab Compared to Various Standard-of-Care Therapies in Previously Treated Participants With Recurrent, Advanced or Metastatic Gastric Cancer or Gastroesophageal Junction Adenocarcinoma



Status:Not yet recruiting
Conditions:Cancer, Cancer, Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:12/7/2018
Start Date:June 15, 2019
End Date:July 11, 2023
Contact:Recruiting sites have contact information. Please contact the sites directly. If there is no contact information,
Email:Clinical.Trials@bms.com
Phone:please email

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A Randomized, Active-Controlled, Open-Label, Phase 2 Clinical Trial of BMS-986213, in Combination With Various Standard-of-Care Therapeutic Regimens, in Participants With Recurrent, Locally Advanced, or Metastatic Gastric Cancer (GC) or Gastroesophageal Junction (GEJ) Adenocarcinoma

The purpose of this study is to determine the effectiveness of relatlimab plus nivolumab,
alone or in combination with various standard-of-care treatments in participants with gastric
cancer (GC) or gastroesophageal junction (GEJ) adenocarcinoma that has come back or spread to
other places in the body after prior therapy.


For more information regarding Bristol-Myers Squibb Clinical Trial participation, please
visit www.BMSStudyConnect.com

Inclusion Criteria:

- Histologically or cytologically confirmed locally advanced or recurrent or metastatic
GC or GEJ adenocarcinoma that is considered incurable by local therapies such as
radiation or surgery

- Evidence of progressive disease (PD) on at least one prior platinum- and
fluoropyrimidine-containing chemotherapy regimen

- Available tumor tissue for biomarker analysis

Exclusion Criteria:

- Must not have squamous cell or undifferentiated GC or GEJ

- Untreated known central nervous system (CNS) metastases

- Uncontrolled or significant cardiovascular disease

Other protocol defined inclusion/exclusion criteria could apply
We found this trial at
21
sites
Miami, Florida 33136
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Miami, FL
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Allentown, Pennsylvania 18103
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Allentown, PA
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Aurora, Colorado 80045
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Aurora, CO
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Bakersfield, California 93301
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Bakersfield, CA
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Boston, Massachusetts 02111
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Boston, MA
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Chapel Hill, North Carolina 27599
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Chapel Hill, NC
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Charlotte, North Carolina 28203
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Charlotte, NC
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Daphne, Alabama 36526
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Daphne, AL
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Fargo, North Dakota 58122
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from
Fargo, ND
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Fullerton, California 92835
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Fullerton, CA
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Lakewood, Colorado
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Lakewood, CO
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Los Angeles, California 90095
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Los Angeles, CA
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Marietta, Georgia 30060
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Marietta, GA
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New Brunswick, New Jersey 08901
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New Brunswick, NJ
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Redondo Beach, California 90227
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Redondo Beach, CA
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Saint Louis, Missouri 63104
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from
Saint Louis, MO
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Santa Barbara, California 93105
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Santa Barbara, CA
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Sioux Falls, South Dakota 57104
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Sioux Falls, SD
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Tampa, Florida 33612
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Tampa, FL
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Vancouver, Washington
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Vancouver, WA
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526 Belgrano
Viedma, Rio Negro R8500
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from
Viedma,
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