Protein Source on Plasma Amino Acid Concentrations
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 25 - 39 |
| Updated: | 3/23/2019 |
| Start Date: | August 24, 2018 |
| End Date: | July 31, 2019 |
| Contact: | Joshua L Hudson, PhD |
| Email: | Hudson67@purdue.edu |
| Phone: | 7654948236 |
Effect of Consuming Ounce Equivalent Portions of Fresh Pork Versus Nuts, Beans, and Eggs as Defined by the Dietary Guidelines for Americans on Essential Amino Acid Substrate Availability for Protein Anabolism
This study will determine the effect of the same ounce-equivalents of fresh pork versus nuts,
beans, and eggs on postprandial plasma essential amino acid availability in adults. Each
participant will receive all four treatments.
beans, and eggs on postprandial plasma essential amino acid availability in adults. Each
participant will receive all four treatments.
The 2015-2020 Dietary Guidelines for Americans stipulates how much Protein Foods should be
consumed per day and per week as part of a Healthy U.S.-Style Eating Pattern. The predominant
protein sources include lean meats, poultry, and eggs, however, nuts, seeds, and soy products
are also included. Ounce-equivalents (oz-eq) are used as a standard unit of measure to
compare animal to non-animal protein sources. One oz-eq of lean meat (1 oz) is equal to 0.5
oz of nuts (1 oz-eq), 0.25 cups (1 oz-eq) of beans, and one whole egg (1 oz-eq). One
limitation of this unit of measure is that the protein quantity and quality of the foods are
not considered. For example, 1 oz-eq of pork loin contains ~7 g of dietary protein whereas 1
oz-eq of almonds contains 3 g of protein. Consequently, consuming an oz-eq portion of protein
foods from different sources could have different effects on the anabolic response to
feeding. The purpose of this study is to assess the effect of consuming ounce equivalent
portions of fresh pork versus nuts, beans, and eggs on essential amino acid substrate
availability for protein anabolism. While it would seem intuitive that this research would
show that higher protein intakes from pork and egg will lead to higher plasma essential amino
acid responses, this research is paramount to addressing the shortcoming of using oz-eq to
achieve the Dietary Guidelines for Americans recommendations for Protein Foods. This research
will serve as an important resource for future Dietary Guidelines Advisory Committees to
reevaluate the appropriateness of equating animal- and plant-based Protein Foods on the
current ounce-equivalent basis.
consumed per day and per week as part of a Healthy U.S.-Style Eating Pattern. The predominant
protein sources include lean meats, poultry, and eggs, however, nuts, seeds, and soy products
are also included. Ounce-equivalents (oz-eq) are used as a standard unit of measure to
compare animal to non-animal protein sources. One oz-eq of lean meat (1 oz) is equal to 0.5
oz of nuts (1 oz-eq), 0.25 cups (1 oz-eq) of beans, and one whole egg (1 oz-eq). One
limitation of this unit of measure is that the protein quantity and quality of the foods are
not considered. For example, 1 oz-eq of pork loin contains ~7 g of dietary protein whereas 1
oz-eq of almonds contains 3 g of protein. Consequently, consuming an oz-eq portion of protein
foods from different sources could have different effects on the anabolic response to
feeding. The purpose of this study is to assess the effect of consuming ounce equivalent
portions of fresh pork versus nuts, beans, and eggs on essential amino acid substrate
availability for protein anabolism. While it would seem intuitive that this research would
show that higher protein intakes from pork and egg will lead to higher plasma essential amino
acid responses, this research is paramount to addressing the shortcoming of using oz-eq to
achieve the Dietary Guidelines for Americans recommendations for Protein Foods. This research
will serve as an important resource for future Dietary Guidelines Advisory Committees to
reevaluate the appropriateness of equating animal- and plant-based Protein Foods on the
current ounce-equivalent basis.
Inclusion Criteria:
- Male or female
- Age 25-39
- BMI 25-35 kg∙m-2
- Weight stable (± 4.5 kg) 3 months pre-study
- Not acutely ill
- Not diabetic
- Not pregnant or lactating
- Not currently (or within 3 months pre-study) following a vigorous exercise regimen
- Non-smoking
- Willing to consume study foods and travel to testing facilities.
We found this trial at
1
site
West Lafayette, Indiana 47907
Principal Investigator: Wayne Campbell, PhD
Phone: 765-496-6342
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