Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity



Status:Recruiting
Conditions:Obesity Weight Loss, Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:45 - Any
Updated:4/4/2019
Start Date:October 24, 2018
End Date:September 28, 2023
Contact:Novo Nordisk
Email:clinicaltrials@novonordisk.com
Phone:(+1) 866-867-7178

Use our guide to learn which trials are right for you!

SELECT - Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity

The researchers are doing the study to see if semaglutide may reduce the risk of having
cardiovascular events in patients with overweight or obesity and with prior cardiovascular
disease. The participant will either get semaglutide (active medicine) or placebo ("dummy"
medicine). Which treatment the participants get is decided by chance. The participant's
chance of getting semaglutide or placebo is the same. The participant will get the study
medicine in a pen. The participants will need to use the pen to inject the study medicine in
a skinfold once a week. The study will last for about 2.5 to 5 years. Participants will have
up to 25 clinic visits with the study doctor.


Inclusion Criteria: - Male or female, age greater than or equal to 45 years at the time of
signing informed consent - Body mass index (BMI) greater than or equal to 27 kg/m^2 - Have
established cardiovascular (CV) disease as evidenced by at least one of the following:
prior myocardial infarction; prior stroke (ischemic or haemorrhagic stroke); or symptomatic
peripheral arterial disease (PAD), as evidenced by intermittent claudication with
ankle-brachial index (ABI) less than 0.85 (at rest), or peripheral arterial
revascularization procedure, or amputation due to atherosclerotic disease Exclusion
Criteria: - Any of the following: myocardial infarction, stroke, hospitalisation for
unstable angina pectoris or transient ischaemic attack within the past 60 days prior to the
day of screening - HbA1c greater than or equal to 48 mmol/mol (6.5 %) as measured by the
central laboratory at screening - History of type 1 or type 2 diabetes (history of
gestational diabetes is allowed)
We found this trial at
153
sites
Monument, Colorado 80132
?
mi
from
Monument, CO
Click here to add this to my saved trials
Albany, New York 12208
?
mi
from
Albany, NY
Click here to add this to my saved trials
Alexandria, Louisiana 71301
?
mi
from
Alexandria, LA
Click here to add this to my saved trials
?
mi
from
Algiers,
Click here to add this to my saved trials
Amarillo, Texas 79106
?
mi
from
Amarillo, TX
Click here to add this to my saved trials
Anderson, Indiana 46011
?
mi
from
Anderson, IN
Click here to add this to my saved trials
Anderson, South Carolina 29621
?
mi
from
Anderson, SC
Click here to add this to my saved trials
Ann Arbor, Michigan 48106
?
mi
from
Ann Arbor, MI
Click here to add this to my saved trials
Arlington, Texas 76012
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Arlington Heights, Illinois 60004
?
mi
from
Arlington Heights, IL
Click here to add this to my saved trials
Atlanta, Georgia 30318
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Aurora, Colorado 80010
?
mi
from
Aurora, CO
Click here to add this to my saved trials
Austin, Texas 78731
?
mi
from
Austin, TX
Click here to add this to my saved trials
Avon, Indiana 46123
?
mi
from
Avon, IN
Click here to add this to my saved trials
Baltimore, Maryland 21229
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Bellaire, Texas 77401
?
mi
from
Bellaire, TX
Click here to add this to my saved trials
Belzoni, Mississippi 39038
?
mi
from
Belzoni, MS
Click here to add this to my saved trials
Beverly Hills, California 90211
?
mi
from
Beverly Hills, CA
Click here to add this to my saved trials
Birmingham, Alabama 35215
?
mi
from
Birmingham, AL
Click here to add this to my saved trials
Boca Raton, Florida 33433
?
mi
from
Boca Raton, FL
Click here to add this to my saved trials
Boston, Massachusetts 02115
?
mi
from
Boston, MA
Click here to add this to my saved trials
Bountiful, Utah 84010
?
mi
from
Bountiful, UT
Click here to add this to my saved trials
Bradenton, Florida 34201
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
Bridgeport, Connecticut 06610
?
mi
from
Bridgeport, CT
Click here to add this to my saved trials
Bristol, Tennessee 37620
?
mi
from
Bristol, TN
Click here to add this to my saved trials
Brooklyn, New York 11215
?
mi
from
Brooklyn, NY
Click here to add this to my saved trials
Butte, Montana 59701
?
mi
from
Butte, MT
Click here to add this to my saved trials
Canton, Michigan 48187
?
mi
from
Canton, MI
Click here to add this to my saved trials
Chapel Hill, North Carolina 27599
?
mi
from
Chapel Hill, NC
Click here to add this to my saved trials
Charleston, South Carolina 29407
?
mi
from
Charleston, SC
Click here to add this to my saved trials
Charlotte, North Carolina 28277
?
mi
from
Charlotte, NC
Click here to add this to my saved trials
Chesapeake, Virginia 23321
?
mi
from
Chesapeake, VA
Click here to add this to my saved trials
Chicago, Illinois 60612
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Cincinnati, Ohio 45229
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Cleveland, Ohio 44106
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Colorado Springs, Colorado 80910
?
mi
from
Colorado Springs, CO
Click here to add this to my saved trials
Corvallis, Oregon 97330
?
mi
from
Corvallis, OR
Click here to add this to my saved trials
Costa Mesa, California 92627
?
mi
from
Costa Mesa, CA
Click here to add this to my saved trials
Crystal River, Florida 34429
?
mi
from
Crystal River, FL
Click here to add this to my saved trials
Cumming, Georgia 30041
?
mi
from
Cumming, GA
Click here to add this to my saved trials
Dallas, Texas 75231
?
mi
from
Dallas, TX
Click here to add this to my saved trials
Danville, Pennsylvania 17822
?
mi
from
Danville, PA
Click here to add this to my saved trials
Danville, Virginia 24541
?
mi
from
Danville, VA
Click here to add this to my saved trials
?
mi
from
Dayton, OH
Click here to add this to my saved trials
Doylestown, Pennsylvania 18901
?
mi
from
Doylestown, PA
Click here to add this to my saved trials
East Brunswick, New Jersey 08816
?
mi
from
East Brunswick, NJ
Click here to add this to my saved trials
El Cajon, California 92020
?
mi
from
El Cajon, CA
Click here to add this to my saved trials
Elkridge, Maryland 21075
?
mi
from
Elkridge, MD
Click here to add this to my saved trials
Evanston, Illinois 60201
?
mi
from
Evanston, IL
Click here to add this to my saved trials
Evansville, Indiana 47714
?
mi
from
Evansville, IN
Click here to add this to my saved trials
Festus, Missouri 63028
?
mi
from
Festus, MO
Click here to add this to my saved trials
Fleming Island, Florida 32003
?
mi
from
Fleming Island, FL
Click here to add this to my saved trials
Flint, Michigan 48504
?
mi
from
Flint, MI
Click here to add this to my saved trials
Fort Lauderdale, Florida 33316
?
mi
from
Fort Lauderdale, FL
Click here to add this to my saved trials
Franklin, Indiana 46131
?
mi
from
Franklin, IN
Click here to add this to my saved trials
Garner, North Carolina 27529
?
mi
from
Garner, NC
Click here to add this to my saved trials
Germantown, Tennessee 38138
?
mi
from
Germantown, TN
Click here to add this to my saved trials
Gillespie, Illinois 62033
?
mi
from
Gillespie, IL
Click here to add this to my saved trials
Glendale, Arizona 85306
?
mi
from
Glendale, AZ
Click here to add this to my saved trials
Golden, Colorado 80401
?
mi
from
Golden, CO
Click here to add this to my saved trials
Great Neck, New York 11021
?
mi
from
Great Neck, NY
Click here to add this to my saved trials
Greenfield, Indiana 46140
?
mi
from
Greenfield, IN
Click here to add this to my saved trials
Greenville, North Carolina 27834
?
mi
from
Greenville, NC
Click here to add this to my saved trials
Greenville, South Carolina 29607
?
mi
from
Greenville, SC
Click here to add this to my saved trials
Hammond, Louisiana 70403
?
mi
from
Hammond, LA
Click here to add this to my saved trials
Harleysville, Pennsylvania 19438
?
mi
from
Harleysville, PA
Click here to add this to my saved trials
Henderson, Nevada 89052
?
mi
from
Henderson, NV
Click here to add this to my saved trials
Hollywood, Florida 33024
?
mi
from
Hollywood, FL
Click here to add this to my saved trials
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Iowa City, Iowa 52242
?
mi
from
Iowa City, IA
Click here to add this to my saved trials
Jacksonville, Florida 32207
?
mi
from
Jacksonville, FL
Click here to add this to my saved trials
Jacksonville Beach, Florida 32250
?
mi
from
Jacksonville Beach, FL
Click here to add this to my saved trials
Johnstown, Pennsylvania 15905
?
mi
from
Johnstown, PA
Click here to add this to my saved trials
Kansas City, Kansas 66160
?
mi
from
Kansas City, KS
Click here to add this to my saved trials
Kenosha, Wisconsin 53142
?
mi
from
Kenosha, WI
Click here to add this to my saved trials
Kingsport, Tennessee 37660
?
mi
from
Kingsport, TN
Click here to add this to my saved trials
La Jolla, California 92037
?
mi
from
La Jolla, CA
Click here to add this to my saved trials
Lake Success, New York 11042
?
mi
from
Lake Success, NY
Click here to add this to my saved trials
Lancaster, California 93534
?
mi
from
Lancaster, CA
Click here to add this to my saved trials
Las Vegas, Nevada 89128
?
mi
from
Las Vegas, NV
Click here to add this to my saved trials
Lomita, California 90717
?
mi
from
Lomita, CA
Click here to add this to my saved trials
Longview, Texas 75605
?
mi
from
Longview, TX
Click here to add this to my saved trials
Los Angeles, California 90027
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
Louisville, Kentucky 40213
?
mi
from
Louisville, KY
Click here to add this to my saved trials
?
mi
from
Maumee, OH
Click here to add this to my saved trials
Melrose Park, Illinois 60160
?
mi
from
Melrose Park, IL
Click here to add this to my saved trials
Memphis, Tennessee 38119
?
mi
from
Memphis, TN
Click here to add this to my saved trials
Miami, Florida 33136
?
mi
from
Miami, FL
Click here to add this to my saved trials
Michigan City, Indiana 46360
?
mi
from
Michigan City, IN
Click here to add this to my saved trials
Midlothian, Virginia 23114
?
mi
from
Midlothian, VA
Click here to add this to my saved trials
Montgomery, Alabama 36106
?
mi
from
Montgomery, AL
Click here to add this to my saved trials
Moreno Valley, California 92555
?
mi
from
Moreno Valley, CA
Click here to add this to my saved trials
Morganton, North Carolina 28655
?
mi
from
Morganton, NC
Click here to add this to my saved trials
Mount Pleasant, South Carolina 29464
?
mi
from
Mount Pleasant, SC
Click here to add this to my saved trials
Muncie, Indiana 47304
?
mi
from
Muncie, IN
Click here to add this to my saved trials
Nashua, New Hampshire 03063
?
mi
from
Nashua, NH
Click here to add this to my saved trials
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Natchitoches, Louisiana 71457
?
mi
from
Natchitoches, LA
Click here to add this to my saved trials
New Albany, Indiana 47150
?
mi
from
New Albany, IN
Click here to add this to my saved trials
New York, New York 10029
?
mi
from
New York, NY
Click here to add this to my saved trials
Norfolk, Virginia 23510
?
mi
from
Norfolk, VA
Click here to add this to my saved trials