A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease



Status:Recruiting
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:60 - 85
Updated:4/5/2019
Start Date:April 30, 2018
End Date:October 8, 2021
Contact:There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or
Email:ClinicalTrials.gov@lilly.com
Phone:1-317-615-4559

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Assessment of Safety, Tolerability, and Efficacy of LY3303560 in Early Symptomatic Alzheimer's Disease

The purpose of this study is to evaluate the safety and efficacy of a study drug that targets
an abnormal protein in the brain found in people with Alzheimer's Disease (AD).


Inclusion Criteria:

- Participants must have gradual and progressive change in memory function for >6
months.

- Participants must have a family member or close friend who is with you at least 10
hours per week and can attend study appointments.

Exclusion Criteria:

- Participants must not have significant neurological disease affecting the nervous
system, other than AD, that affects cognition or may affect completion of the study.

- Participants must not have serious or unstable illness that could interfere with the
analysis of the study or has a life expectancy <24 months.

- Participants must not have history of cancer within the last 5 years with the
exception of certain types of skin, cervical, prostate, and other cancers that are not
likely to recur or spread.

- Participants must not have serious risk for suicide.

- Participants must not have history of drug or alcohol use disorder within the last 2
years.

- Participants must not have multiple severe drug allergies

- Participants must not have HIV, Hepatitis B or Hepatitis C

- Participants must not be receiving gamma globulin (IgG) or intravenous immunoglobulin
(IVIG) therapy
We found this trial at
51
sites
1040 North Mason Road
Saint Louis, Missouri 63141
Principal Investigator: Siddharth Kaul
Phone: 636-220-1200
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800 Washington St
Boston, Massachusetts 02111
(617) 636-5000
Principal Investigator: Tinatin Chabrashvili
Phone: 617-636-5000
Tufts Medical Center Tufts Medical Center is an internationally-respected academic medical center – a teaching...
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104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
Principal Investigator: John P. Nardandrea
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Ocala, FL
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2450 E. River Road
Tucson, Arizona 85718
520-320-2147
Principal Investigator: Michael A Badruddoja
Phone: 520-320-2140
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Allentown, Pennsylvania 18104
Principal Investigator: Paul K. Gross
Phone: 610-820-0342
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Atlantis, Florida 33462
Principal Investigator: Mark A Goldstein
Phone: 561-968-2933
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21000 Northeast 28th Avenue
Aventura, Florida 33180
Principal Investigator: Julie Schwartzbard
Phone: 305-933-5993
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Aventura, FL
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Baltimore, Maryland 21208
Principal Investigator: Alan M. Jonas
Phone: 410-602-1440
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Bennington, Vermont 05201
Principal Investigator: Diana Michalczuk
Phone: 802-447-1409
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Chicago, Illinois 60640
Principal Investigator: Jeffrey S. Ross
Phone: 773-275-3500
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Cincinnati, Ohio 45219
Principal Investigator: Robert S Keyes
Phone: 513-585-1777
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Columbus, Georgia 31909
Principal Investigator: Jonathan L Liss
Phone: 706-653-8455
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Columbus, Ohio 43210
Principal Investigator: Douglas W. Scharre
Phone: 614-293-4969
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Dallas, Texas 75231
Principal Investigator: Duc Tran
Phone: 214-750-9977
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Dallas, Texas 75219
Principal Investigator: Claudia Padilla
Phone: 214-820-7665
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3230 Eden Avenue
Dayton, Ohio 45417
Principal Investigator: Lawrence P Goldstick
Phone: 937-495-0000
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Deerfield Beach, Florida 33064
Principal Investigator: Jose E De La Gandara
Phone: 954-786-7331
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Delray Beach, Florida 33445
Principal Investigator: Mark L Brody
Phone: 561-374-8461
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Elk Grove Village, Illinois 60007
Principal Investigator: Ajay Sood
Phone: 847-981-3630
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Encino, California 91316
Principal Investigator: DANIEL E. GROSZ
Phone: 818-705-7451
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100 Eisenhower Drive
Fairfax, Virginia 22031
Principal Investigator: James L Bicksel
Phone: 703-505-8276
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Fort Myers, Florida 33912
Principal Investigator: Wendy Robinson Bond
Phone: 2399397777
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Fullerton, California 92835
Principal Investigator: Jack H. Florin
Phone: 714-738-0800
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Hollywood, Florida 33021
Principal Investigator: Harvey Schwartz
Phone: 954-620-3340
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Houston, Texas 77030
Principal Investigator: Joseph C Masdeu
Phone: 713-441-1150
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Indianapolis, Indiana 46256
Principal Investigator: Kristi George
Phone: 317-537-6056
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Irvine, California 92618
Principal Investigator: Elly R Lee
Phone: 949-753-1663
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Lenexa, Kansas 66214
Principal Investigator: Vernon Rowe
Phone: 913-894-1500
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Los Alamitos, California 90720
Principal Investigator: David A Rosenberg
Phone: 714-827-3668
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Media, Pennsylvania 19063
Principal Investigator: Shivkumar Hatti
Phone: 610-891-9024
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8940 North Kendall Drive
Miami, Florida 33176
Principal Investigator: Victor Faradji
Phone: 305-595-4041
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Newton, Massachusetts 02459
Principal Investigator: Paul R. Solomon
Phone: 617-699-6927
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100 West Gore Street
Orlando, Florida 32806
Principal Investigator: Ira J Goodman
Phone: 407-210-1320
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2010 Wilshire Boulevard
Panorama City, California 91402
Principal Investigator: Parvin D Syal
Phone: 818-532-6880
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Peterborough, Ontario
Principal Investigator: Jennifer Ingram
Phone: 7057493906
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Phoenix, Arizona 85006
Principal Investigator: William Burke
Phone: 602-829-9608
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Port Orange, Florida 32127
Principal Investigator: Alexander J White
Phone: 386-304-7070
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Princeton, New Jersey 08540
Principal Investigator: Jeffrey T Apter
Phone: 609-921-3555
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345 Blackstone Blvd
Providence, Rhode Island 02906
(401) 455-6200
Principal Investigator: Stephen P Salloway
Phone: 401-455-6403
Butler Hospital Founded in 1844, Butler Hospital is the state's only non-profit, free-standing psychiatric hospital...
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Raleigh, North Carolina 27607
Principal Investigator: Bradley J Robottom
Phone: 919-782-3456
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Redlands, California 92374
Principal Investigator: Donald L Anderson
Phone: 909-792-9007
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San Diego, California 92103
Principal Investigator: Stephen Thein
Phone: 619-294-4302
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San Francisco, California 94143
Principal Investigator: Julio Rojas-Martinez
Phone: 415-476-6880
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Santa Ana, California 92705
Principal Investigator: John Duffy
Phone: 714-542-3008
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Springfield, New Jersey 07081
Principal Investigator: Michelle Papka
Phone: 973-850-4622
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Stamford, Connecticut 06905
Principal Investigator: Peter J McAllister
Phone: 203-914-1903
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Stuart, Florida 34997
Principal Investigator: Mark L Brody
Phone: 561-374-8461
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Sunrise, Florida 33351
Principal Investigator: Richard Pete Singer
Phone: 9544758171
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Toms River, New Jersey 08755
Principal Investigator: Sanjiv K Sharma
Phone: 732-341-9500
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Topeka, Kansas 66606
Principal Investigator: Michael Cox
Phone: 785-354-3680
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1901 S Hawthorne Rd #306
Winston-Salem, North Carolina 27103
(336) 768-8062
Principal Investigator: Franklin Giles Crowell
Phone: 336-768-8062
PMG Research of Winston-Salem PMG Research of Winston-Salem, founded in 1979, occupies a 10,000 square...
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