Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Calcineurin Inhibitors (CNIs) to Everolimus



Status:Recruiting
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:18 - 85
Updated:3/9/2019
Start Date:February 1, 2018
End Date:November 1, 2019
Contact:Baljit Kaur
Email:bkaur@kumc.edu
Phone:913-588-3708

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Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Calcineurin Inhibitors to Everolimus

The purpose of this study is to learn if changing from Tacrolimus to Everolimus will improve
cognitive function by having less effect on brain blood flow.


Inclusion Criteria:

- English speaking

- able to sign informed consent

- able to arrange transportation to and from study site

- without acute stroke, concussion or traumatic brain injury

- without acute medical issues at the time of participation

- after 12 weeks of the liver transplant surgery

Exclusion Criteria:

- are claustrophobic or have other contra-indication for magnetic resonance imaging
(MRI)

- have hearing or visual impairment

- are unable to read, write, speak or understand English

- have uncontrolled psychosis or seizure disorder or are currently using antipsychotics
or anti-epileptics

- within 12 weeks after transplant
We found this trial at
1
site
3901 Rainbow Blvd
Kansas City, Kansas 66160
(913) 588-5000
University of Kansas Medical Center The University of Kansas Medical Center serves Kansas through excellence...
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Kansas City, KS
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