Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults



Status:Not yet recruiting
Healthy:No
Age Range:25 - 60
Updated:3/23/2019
Start Date:June 2019
End Date:September 2020
Contact:Richard D Mattes, PhD
Email:mattes@purdue.edu
Phone:765-494-0662

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Assess the impact of 100% grape juice with a meal on postprandial glycemic response and
subsequent appetite, food intake and cognitive function.

Investigators earlier studies and published literature suggest that the phenolic content and
strong flavor intensity of 100% Concord grape juice hold potential beneficial effects on
blood sugar levels. Investigators aim to better understand the consumption of 100% grape
juice with a meal modifies appetite and glycemia acutely and over the day using a 24 hour
glucose monitor.

Inclusion Criteria:

- BMI between 25.0-34.9 kg/m2

- Willingness to eat all test foods

- Low consumer of tea and coffee, willingness to refrain from both during the 48 hours
prior to test days and on the test day

- Fasting blood glucose below 6.1mmol/l via capillary finger-stick blood sample using a
SureStep glucometer (Lifescan, Milpitas, CA)

Exclusion Criteria:

- Taking medications known to affect glycemia, lipid metabolism or appetite

- Body weight fluctuation of >5kg in the past 3 months

- Taking vitamin or other supplements

- Smokers

- Acute or Chronic disease
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Phone: 765-494-0662
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